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  Indian J Med Microbiol
 

Figure 2: Effects of OPA on FCA-induced alterations in antioxidant parameters, i.e., SOD (a), GSH (b), MDA (c) and NO (d) as well as pro-inflammatory cytokines levels, i.e., TNF-α (e), IL-1 β (f), IL-6 (g), and IL-17 (h) in synovial tissues. Values in parentheses indicate a dose in mg/kg (n = 6). Data were analyzed by one-way ANOVA followed by Tukey's multiple comparisons test. For comparison with AIA-control group: *P < 0.05, comparison with normal group: #P < 0.05 and comparison with one another: $p < 0.05. AIA: Adjuvant-induced arthritis, LF: Leflunomide; OPA: Oxypaeoniflorin; SOD: Superoxide dismutase; GSH: Glutathione Peroxidase; MDA: Malondialdehyde; NO: Nitric Oxide; TNF-α: Tumor necrosis factor-alpha; ILs: Interleukins

Figure 2: Effects of OPA on FCA-induced alterations in antioxidant parameters, i.e., SOD (a), GSH (b), MDA (c) and NO (d) as well as pro-inflammatory cytokines levels, i.e., TNF-α (e), IL-1 β (f), IL-6 (g), and IL-17 (h) in synovial tissues. Values in parentheses indicate a dose in mg/kg (<i>n</i> = 6). Data were analyzed by one-way ANOVA followed by Tukey's multiple comparisons test. For comparison with AIA-control group: *<i>P</i> < 0.05, comparison with normal group: <sup>#</sup><i>P</i> < 0.05 and comparison with one another: <sup>$</sup><i>p</i> < 0.05. AIA: Adjuvant-induced arthritis, LF: Leflunomide; OPA: Oxypaeoniflorin; SOD: Superoxide dismutase; GSH: Glutathione Peroxidase; MDA: Malondialdehyde; NO: Nitric Oxide; TNF-α: Tumor necrosis factor-alpha; ILs: Interleukins