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  Indian J Med Microbiol
 

Figure 2: Effects of tanshinone IIA on the apoptosis of SH-SY5Y cells injured by Aβ25–35. After treating with sodium 4-phenylbutyrate (5 mM) or indicated concentrations of tanshinone IIA, the apoptosis of Aβ25–35-injured SH-SY5Y cells was measure by (a) TUNEL assay, (b) flow cytometry with Annexin V/PI Staining and (c) Western Blot for apoptosis pathway, including Bax and Bcl-2. Statistical data are presented as mean ± standard deviation **P < 0.01, versus control group. #P < 0.05, ##P < 0.01, versus Aβ group. The experiments were independently repeated three times

Figure 2: Effects of tanshinone IIA on the apoptosis of SH-SY5Y cells injured by Aβ<sub>25–35</sub>. After treating with sodium 4-phenylbutyrate (5 mM) or indicated concentrations of tanshinone IIA, the apoptosis of Aβ<sub>25–35</sub>-injured SH-SY5Y cells was measure by (a) TUNEL assay, (b) flow cytometry with Annexin V/PI Staining and (c) Western Blot for apoptosis pathway, including Bax and Bcl-2. Statistical data are presented as mean ± standard deviation **<i>P</i> < 0.01, versus control group. <sup>#</sup><i>P</i> < 0.05, <sup>##</sup><i>P</i> < 0.01, versus Aβ group. The experiments were independently repeated three times