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  Indian J Med Microbiol
 

Figure 1: Effects of tanshinone IIA on the proliferation of SH-SY5Y cells injured by Aβ25–35. (a) Chemical structure of tanshinone IIA. After treating with sodium 4-phenylbutyrate (5 mM) or tanshinone IIA (2.5 μM, 5 μM, and 10 μM), the proliferation of Aβ25–35-injured SH-SY5Y cells was measure by (b) CCK8 assay, (c) EdU staining, and (d) Western blot for cell proliferation factor (Ki-67 and PCNA). Statistical data are presented as mean ± standard deviation **P < 0.01, versus control group. #P < 0.05, ##P < 0.01, versus Aβ group. The experiments were independently repeated three times

Figure 1: Effects of tanshinone IIA on the proliferation of SH-SY5Y cells injured by Aβ<sub>25–35</sub>. (a) Chemical structure of tanshinone IIA. After treating with sodium 4-phenylbutyrate (5 mM) or tanshinone IIA (2.5 μM, 5 μM, and 10 μM), the proliferation of Aβ<sub>25–35</sub>-injured SH-SY5Y cells was measure by (b) CCK8 assay, (c) EdU staining, and (d) Western blot for cell proliferation factor (Ki-67 and PCNA). Statistical data are presented as mean ± standard deviation **<i>P</i> < 0.01, versus control group. <sup>#</sup><i>P</i> < 0.05, <sup>##</sup><i>P</i> < 0.01, versus Aβ group. The experiments were independently repeated three times