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  Indian J Med Microbiol
 

Figure 4: The effect of aqueous extract of Cucurbita pepo on the expression of ionized calcium-binding adaptor molecule-1 immunohistochemical staining was performed in brain cortical tissue slices (×20). Positive cells are observed as black/brown dots. (a) In control group, ionized calcium-binding adaptor molecule-1 expression was insignificant. (b) Strong ionized calcium-binding adaptor molecule-1 immunopositivity in lipopolysaccharide-induced toxicity in mice brain. (c) Mice that received lipopolysaccharide + aqueous extract of Cucurbita pepo showed 25%–40% less immunopositive cells compared to inducer group. (d) Group of mice that received aqueous extract of Cucurbita pepo alone almost similar to normal control group. Statistically significant (P > 0.05) results were presented. Values compared a with b. b with c and d

Figure 4: The effect of aqueous extract of <i>Cucurbita pepo</i> on the expression of ionized calcium-binding adaptor molecule-1 immunohistochemical staining was performed in brain cortical tissue slices (×20). Positive cells are observed as black/brown dots. (a) In control group, ionized calcium-binding adaptor molecule-1 expression was insignificant. (b) Strong ionized calcium-binding adaptor molecule-1 immunopositivity in lipopolysaccharide-induced toxicity in mice brain. (c) Mice that received lipopolysaccharide + aqueous extract of <i>Cucurbita pepo</i> showed 25%–40% less immunopositive cells compared to inducer group. (d) Group of mice that received aqueous extract of <i>Cucurbita pepo</i> alone almost similar to normal control group. Statistically significant (<i>P</i> > 0.05) results were presented. Values compared a with b. b with c and d