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  Indian J Med Microbiol
 

Figure 8: (a and b) Histopathological analysis of colon tissues of control and experimental animals. (a) Control animals displayed the undamaged normal tissue architecture (Group-I). dextran sulfate sodium-provoked animals revealed the escalated neutrophil infiltration, severe inflammation and ulceration in the colon tissues (Group-II). Deguelin-supplemented colitic mice displayed the almost normal tissue architecture with a very minimal sore (Group-III). Sulfasalazine-treated mice showed near-normal tissue structures (Group-IV). (b) Showing the graphical representation of histological changes in the colon tissues of experimental animals. All values are depicted as mean ± standard deviation (n = 6). The level of statistical significance was calculated by one-way ANOVA followed by the DMRT test; note: *P < 0.05 when compared with the control group and **P < 0.05 when compared with dextran sulfate sodium-treated group

Figure 8: (a and b) Histopathological analysis of colon tissues of control and experimental animals. (a) Control animals displayed the undamaged normal tissue architecture (Group-I). dextran sulfate sodium-provoked animals revealed the escalated neutrophil infiltration, severe inflammation and ulceration in the colon tissues (Group-II). Deguelin-supplemented colitic mice displayed the almost normal tissue architecture with a very minimal sore (Group-III). Sulfasalazine-treated mice showed near-normal tissue structures (Group-IV). (b) Showing the graphical representation of histological changes in the colon tissues of experimental animals. All values are depicted as mean ± standard deviation (<i>n</i> = 6). The level of statistical significance was calculated by one-way ANOVA followed by the DMRT test; note: *<i>P</i> < 0.05 when compared with the control group and **<i>P</i> < 0.05 when compared with dextran sulfate sodium-treated group