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  Indian J Med Microbiol
 

Figure 1: Effects of salidroside on apoptosis, autophagy and mitogen-activated protein kinases pathway in GC cells. The CCK-8 viability assay (a), Terminal transferees dUTP nick end labeling apoptosis detection (b), apoptotic rate using a FITC Annexin V apoptosis detection kit using flow cytometry (c), the expressions of Bax, Bcl-2, p-p38, p38, p-ERK1/2, ERK1/2, p-JNK, JNK, LC3-I, LC3-II, and Beclin-1 (d and e) and the formation of autophagic vacuoles as determined by immunofluorescent staining for LC3 (f) in salidroside-treated BGC-823 cells. Statistically significant differences were indicated (*P < 0.05, **P < 0.01, ***P < 0.001)

Figure 1: Effects of salidroside on apoptosis, autophagy and mitogen-activated protein kinases pathway in GC cells. The CCK-8 viability assay (a), Terminal transferees dUTP nick end labeling apoptosis detection (b), apoptotic rate using a FITC Annexin V apoptosis detection kit using flow cytometry (c), the expressions of Bax, Bcl-2, p-p38, p38, p-ERK1/2, ERK1/2, p-JNK, JNK, LC3-I, LC3-II, and Beclin-1 (d and e) and the formation of autophagic vacuoles as determined by immunofluorescent staining for LC3 (f) in salidroside-treated BGC-823 cells. Statistically significant differences were indicated (*<i>P</i> < 0.05, **<i>P</i> < 0.01, ***<i>P</i> < 0.001)