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  Indian J Med Microbiol
 

Figure 1: Effect of Bilobalide on reduces cecal ligation and puncture-induced inflammatory response in septic mice. The normal alveolar tissue architecture and no inflammatory conditions were noted in control (Group I). The excessive inflammatory cells infiltration, alveolar damages, and edema were noted in sepsis-induced mice (Group II). Bilobalide (20, 40, and 80 mg/kg) pretreatment repressed the inflammatory cell permeation and histopathological alterations in the lungs (Group III-V). Values were depicted as a mean ± standard deviation of triplicates (n = 6). The significance level was determined by using Kruskal–Wallis test. Note: * indicates P < 0.05 when compared with control; “#” indicates P < 0.05 when compared with the sepsis-induced group. Histological alterations were pointed out by using arrow marks

Figure 1: Effect of Bilobalide on reduces cecal ligation and puncture-induced inflammatory response in septic mice. The normal alveolar tissue architecture and no inflammatory conditions were noted in control (Group I). The excessive inflammatory cells infiltration, alveolar damages, and edema were noted in sepsis-induced mice (Group II). Bilobalide (20, 40, and 80 mg/kg) pretreatment repressed the inflammatory cell permeation and histopathological alterations in the lungs (Group III-V). Values were depicted as a mean ± standard deviation of triplicates (<i>n</i> = 6). The significance level was determined by using Kruskal–Wallis test. Note: <sup>”</sup>*<sup>”</sup> indicates <i>P</i> < 0.05 when compared with control; “#” indicates <i>P</i> < 0.05 when compared with the sepsis-induced group. Histological alterations were pointed out by using arrow marks