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  Indian J Med Microbiol
 

Figure 6: Effects of BJIT on overexpressed TRPM7 or TMEM16A in HEK 293 cells. (a) BJIT blocked overexpressed TRPM7 currents. (b) Current-voltage relationships were measured before (1) and during (2) treatment. (d) BJIT blocked the overexpressed TMEM16A currents. (e) Current-voltage relationships were measured before (1) and during (2) treatment. Responses to BJIT during overexpressed (c) TRPM7 or (f ) TMEM16A are summarized. **P < 0.01. A01 (a selective TMEM16A inhibitor): A positive control. BJIT: Bojungikki-tang; TRPM7: Transient receptor potential melastatin 7; HEK: Human embryonic kidney; A01, T16Ainh-A01; TMEM16A: Transmembrane protein 16A

Figure 6: Effects of BJIT on overexpressed TRPM7 or TMEM16A in HEK 293 cells. (a) BJIT blocked overexpressed TRPM7 currents. (b) Current-voltage relationships were measured before (1) and during (2) treatment. (d) BJIT blocked the overexpressed TMEM16A currents. (e) Current-voltage relationships were measured before (1) and during (2) treatment. Responses to BJIT during overexpressed (c) TRPM7 or (f ) TMEM16A are summarized. **<i>P</i> < 0.01. A01 (a selective TMEM16A inhibitor): A positive control. BJIT: Bojungikki-tang; TRPM7: Transient receptor potential melastatin 7; HEK: Human embryonic kidney; A01, T16Ainh-A01; TMEM16A: Transmembrane protein 16A