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  Indian J Med Microbiol
 

Figure 5: The histopathological changes of the cross section of the rat colon stained with hematoxylin and eosin. The colon of control (a) and betulin (d) alone-treated rat showing normal architecture with mucosal and submucosal layers. Whereas, colon of a 1,2-dimethylhydrazine (b) alone-treated rat was showed proliferating mucosal glands with severe dysplastic changes representing transformation to carcinoma. The colon of 1,2-dimethylhydrazine with betulin (c)-treated rat showing glands within normal limits

Figure 5: The histopathological changes of the cross section of the rat colon stained with hematoxylin and eosin. The colon of control (a) and betulin (d) alone-treated rat showing normal architecture with mucosal and submucosal layers. Whereas, colon of a 1,2-dimethylhydrazine (b) alone-treated rat was showed proliferating mucosal glands with severe dysplastic changes representing transformation to carcinoma. The colon of 1,2-dimethylhydrazine with betulin (c)-treated rat showing glands within normal limits