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  Indian J Med Microbiol
 

Figure 3: Effects of cCN and Dox on the mRNA expression of intrinsic and extrinsic signaling molecules in MDA-MD-231 cells. Cells were treated with IC50 concentrations of cCN and Dox for 48 h. The mRNA expression of apoptosis-related genes was analyzed by qPCR using SYBR Green method. Target gene expression was normalized to GAPDH mRNA expression, and the results were expressed as log2 (2−ΔΔCt) fold change relative to control (untreated cells). Data represent mean ± SD from two independent experiments (n = 2). *P ≤ 0.05 versus control

Figure 3: Effects of cCN and Dox on the mRNA expression of intrinsic and extrinsic signaling molecules in MDA-MD-231 cells. Cells were treated with IC<sub>50</sub> concentrations of cCN and Dox for 48 h. The mRNA expression of apoptosis-related genes was analyzed by qPCR using SYBR Green method. Target gene expression was normalized to <i>GAPDH</i> mRNA expression, and the results were expressed as log2 (2<sup>−ΔΔCt</sup>) fold change relative to control (untreated cells). Data represent mean ± SD from two independent experiments (<i>n</i> = 2). *<i>P</i> ≤ 0.05 versus control