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  Indian J Med Microbiol
 

Figure 8: Representation of anti-neuroinflammatory mechanism of glabridin in lipopolysaccharide-induced microglia through the prevention of nuclear factor-κB activation. Glabridin prevented the proteosomal degradation of IκB complex thereby inhibited the translocation of nuclear factor-κB subunits into nucleus thus suppressed the activation of gene expression encoded for pro-inflammatory proteins

Figure 8: Representation of anti-neuroinflammatory mechanism of glabridin in lipopolysaccharide-induced microglia through the prevention of nuclear factor-κB activation. Glabridin prevented the proteosomal degradation of IκB complex thereby inhibited the translocation of nuclear factor-κB subunits into nucleus thus suppressed the activation of gene expression encoded for pro-inflammatory proteins