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Figure 4: Caspases activation by isoliquiritigenin in 5637 cells. (a) 5637 cells were lysed and lysates were assayed for caspase-3 and -9 activities. (b) The changes of caspase-3, -9, and PARP cleavage activity were investigated by western blot. Results are presented as mean ± standard error of the mean GAPDH was the loading control. ISL: Isoliquiritigenin; CTRL: Control; PARP: Poly (adenosine diphosphate-ribose) polymerase. *P < 0.05, **P < 0.01 versus untreated controls |
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