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  Indian J Med Microbiol
 

Figure 5: Histone acetylation was involved in the suppressive effects of narirutin on interferon-gamma-inducible protein-10 production in monocyte-derived M1 cells. Narirutin at 10-6 M suppressed lipopolysaccharide-induced acetylation of histone H3 (a) and H4 (b) acetylation in the interferon-gamma-inducible protein-10 promoter region in M1 cells. Data are presented as mean ± standard deviation values of triplicate measurements of three independent experiments. ***P < 0.001 for between groups with and without narirutin pretreatment

Figure 5: Histone acetylation was involved in the suppressive effects of narirutin on interferon-gamma-inducible protein-10 production in monocyte-derived M1 cells. Narirutin at 10<sup>-6</sup> M suppressed lipopolysaccharide-induced acetylation of histone H3 (a) and H4 (b) acetylation in the interferon-gamma-inducible protein-10 promoter region in M1 cells. Data are presented as mean ± standard deviation values of triplicate measurements of three independent experiments. ***<i>P</i> < 0.001 for between groups with and without narirutin pretreatment