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  Indian J Med Microbiol
 

Figure 3: The inhibition of interferon-gamma-inducible protein-10 production in M1 macrophages by narirutin was partly reversed by peroxisome proliferator-activated receptor-a and peroxisome proliferator-activated receptor-γ antagonist in 24 h (a and c) or 48 h (b and d) after lipopolysaccharide pretreatment. Moreover, this regulation effect of interferon-gamma-inducible protein-10 in narirutin could be regulated through both peroxisome proliferator-activated receptor-a and peroxisome proliferator-activated receptor-γ at a higher level (10-5 M). Data are presented as mean ± standard deviation values of triplicate measurements of three independent experiments. *P < 0.05 and **P < 0.01 between groups with and without peroxisome proliferator-activated receptor-a antagonist/peroxisome proliferator-activated receptor-α antagonist treatment

Figure 3: The inhibition of interferon-gamma-inducible protein-10 production in M1 macrophages by narirutin was partly reversed by peroxisome proliferator-activated receptor-a and peroxisome proliferator-activated receptor-γ antagonist in 24 h (a and c) or 48 h (b and d) after lipopolysaccharide pretreatment. Moreover, this regulation effect of interferon-gamma-inducible protein-10 in narirutin could be regulated through both peroxisome proliferator-activated receptor-a and peroxisome proliferator-activated receptor-γ at a higher level (10<sup>-5</sup> M). Data are presented as mean ± standard deviation values of triplicate measurements of three independent experiments. *<i>P</i> < 0.05 and **<i>P</i> < 0.01 between groups with and without peroxisome proliferator-activated receptor-a antagonist/peroxisome proliferator-activated receptor-α antagonist treatment