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  Indian J Med Microbiol
 

Figure 3: Effect of the acute treatment of MMS (50–1000 mg/kg, p.o.), METH (0.5 mg/kg, intraperitoneally), and CLZ (1 mg/kg, p.o.) on the spontaneous locomotor activity in mice. Values are expressed as mean ± SEM (n = 8). The statistical differences between the treatment groups (MMS and METH) and vehicle control groups (CMC and SAL) were analyzed using one-way ANOVA followed by post hoc Dunnett's multiple comparison test. MMS: Methanolic extract of Mitragyna speciosa; METH: Methamphetamine; CLZ: Clozapine; CMC: Carboxy methyl cellulose; SAL: Saline; CPP: Conditioned place preference; SEM: Standard error of the mean

Figure 3: Effect of the acute treatment of MMS (50–1000 mg/kg, p.o.), METH (0.5 mg/kg, intraperitoneally), and CLZ (1 mg/kg, p.o.) on the spontaneous locomotor activity in mice. Values are expressed as mean ± SEM (<i>n</i> = 8). The statistical differences between the treatment groups (MMS and METH) and vehicle control groups (CMC and SAL) were analyzed using one-way ANOVA followed by <i>post hoc</i> Dunnett's multiple comparison test. MMS: Methanolic extract of <i>Mitragyna speciosa</i>; METH: Methamphetamine; CLZ: Clozapine; CMC: Carboxy methyl cellulose; SAL: Saline; CPP: Conditioned place preference; SEM: Standard error of the mean