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  Indian J Med Microbiol
 

Figure 2: The effect of MMS per se on place preference in mice. (a) The data represent the differences between the times spent in the compartment associated with drugs (MMS/METH/CLZ) and vehicles (CMC/SAL). The negative values represent a preference for the black compartment and vice versa. (b) The number of line crossings in CPP box. Each bar represents the mean ± SEM (n = 8). Statistical significance was observed at **P < 0.01 when compared between pre- and post-conditioning scores. MMS: Methanolic extract of Mitragyna speciosa; METH: Methamphetamine; CLZ: Clozapine; CMC: Carboxy methyl cellulose; SAL: Saline; CPP: Conditioned place preference; SEM: Standard error of the mean

Figure 2: The effect of MMS <i>per se</i> on place preference in mice. (a) The data represent the differences between the times spent in the compartment associated with drugs (MMS/METH/CLZ) and vehicles (CMC/SAL). The negative values represent a preference for the black compartment and vice versa. (b) The number of line crossings in CPP box. Each bar represents the mean ± SEM (<i>n</i> = 8). Statistical significance was observed at **<i>P</i> < 0.01 when compared between pre- and post-conditioning scores. MMS: Methanolic extract of <i>Mitragyna speciosa</i>; METH: Methamphetamine; CLZ: Clozapine; CMC: Carboxy methyl cellulose; SAL: Saline; CPP: Conditioned place preference; SEM: Standard error of the mean