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  Indian J Med Microbiol
 

Figure 3: Effect Glycyrrhiza glabra extracts on pro-inflammatory cytokines in the lung tissues of lipopolysaccharide-induced acute lung injury mice were detected by quantifying the expression of messenger ribonucleic acid. Levels of pro-inflammatory cytokines such as tumor necrosis factor-<Symbol>α</Symbol> (a), interleukin-1<Symbol>β</Symbol> (b), and interleukin-6 (c) were determined after 24 h of treatment with dexamethasone or Glycyrrhiza glabra extract. The values shown in the figures are the average values ± standard deviation (n = 5). *P < 0.01 versus control group; **P < 0.05 versus LPG group. Where NS: Normal saline group; LPS: Lipopolysaccharide group; DEX: Dexamethasone group; GGEC: Glycyrrhiza glabra extract control group; GGE200: Glycyrrhiza glabra extract group treated with plant extract at the dosage of 200mg/kg body weight; GGE400: Glycyrrhiza glabra extract group treated with plant extract at the dosage of 400 mg/kg body weight; TNF-α: Tumour necrosis factor-alpha; IL-1β: Interleukin 1 beta; IL 6: Interleukin 6

Figure 3: Effect <i>Glycyrrhiza glabra</i> extracts on pro-inflammatory cytokines in the lung tissues of lipopolysaccharide-induced acute lung injury mice were detected by quantifying the expression of messenger ribonucleic acid. Levels of pro-inflammatory cytokines such as tumor necrosis factor-<Symbol>α</Symbol> (a), interleukin-1<Symbol>β</Symbol> (b), and interleukin-6 (c) were determined after 24 h of treatment with dexamethasone or <i>Glycyrrhiza glabra</i> extract. The values shown in the figures are the average values ± standard deviation (<i>n</i> = 5).  *<i>P</i> < 0.01 versus control group; **<i>P </i>< 0.05 versus LPG group. Where NS: Normal saline group; LPS: Lipopolysaccharide group; DEX: Dexamethasone group; GGEC: <i>Glycyrrhiza glabra</i> extract control group; GGE200: <i>Glycyrrhiza glabra</i> extract group treated with plant extract at the dosage of 200mg/kg body weight; GGE400: <i>Glycyrrhiza glabra</i> extract group treated with plant extract at the dosage of 400 mg/kg body weight; TNF-α: Tumour necrosis factor-alpha; IL-1β: Interleukin 1 beta; IL 6: Interleukin 6