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  Indian J Med Microbiol
 

Figure 4: Effect of Ecklonia cava polyphenols on aldose reductase activity in the sciatic nerve of diabetic animals. Full length tibial sciatic nerves were isolated from the respective animal groups and homogenized. The aldose reductase enzymatic activity in the homogenates of respective groups was determined. Epalrestat, an AR inhibitor, was used as a positive control. Values are expressed as a mean ± standard error of the mean (n = 6). ***P < 0.001 compared with normal controls, ###P < 0.001, ##P < 0.01 compared with diabetic peripheral neuropathy control

Figure 4: Effect of <i>Ecklonia cava</i> polyphenols on aldose reductase activity in the sciatic nerve of diabetic animals. Full length tibial sciatic nerves were isolated from the respective animal groups and homogenized. The aldose reductase enzymatic activity in the homogenates of respective groups was determined. Epalrestat, an AR inhibitor, was used as a positive control. Values are expressed as a mean ± standard error of the  mean (<i>n</i> = 6). ***<i>P</i> < 0.001 compared with normal controls, ###<i>P</i> < 0.001, ##<i>P</i> < 0.01 compared with diabetic peripheral neuropathy control