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  Indian J Med Microbiol
 

Figure 5: Effect of Erigeron linifolius hydroalcoholic extract in lipopolysachharide-challenged animals on hippocampal mRNA expression of (a) Nuclear factor-kappa B phosphor 65 (b) Caspase-3, (c) Nuclear-related factor 2, and GAPDH (d). (a) Lane 1 – marker, (b) Lane 1 – normal control, (c) Lane 2 – lipopolysachharide, (d) Lane 3 – imipramine + lipopolysachharide, (e) Lane 4 – Erigeron linifolius hydroalcoholic extract 100 + lipopolysachharide, (f) Lane 5 – Erigeron linifolius hydroalcoholic extract 200 + lipopolysachharide. Data are expressed as “fold changes” as compared with normal control. Values represent mean ± standard error of mean (n = 3) in each group. Statistical significance was determined by one-way analysis of variance followed by Tukey's post hoc test. ##P < 0.01 compared with normal control. *P < 0.05; **P < 0.01 compared with lipopolysachharide-challenged group

Figure 5: Effect of <i>Erigeron linifolius</i> hydroalcoholic extract in lipopolysachharide-challenged animals on hippocampal mRNA expression of (a) Nuclear factor-kappa B phosphor 65 (b) Caspase-3, (c) Nuclear-related factor 2, and GAPDH (d). (a) Lane 1 – marker, (b) Lane 1 – normal control, (c) Lane 2 – lipopolysachharide, (d) Lane 3 – imipramine + lipopolysachharide, (e) Lane 4 – <i>Erigeron linifolius</i> hydroalcoholic extract 100 + lipopolysachharide, (f) Lane 5 – <i>Erigeron linifolius</i> hydroalcoholic extract 200 + lipopolysachharide. Data are expressed as “fold changes” as compared with normal control. Values represent mean ± standard error of mean (<i>n</i> = 3) in each group. Statistical significance was determined by one-way analysis of variance followed by Tukey's <i>post hoc</i> test. ##<i>P</i> < 0.01 compared with normal control. *<i>P</i> < 0.05; **<i>P</i> < 0.01 compared with lipopolysachharide-challenged group