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  Indian J Med Microbiol
 

Figure 2: Morphological changes induced by chlorpyrifos at 50 (b), 75 (c) and 150 (d) μM concentrations in rat hepatocytes primary culture compared to control (a) hepatocytes (dimethyl sulfoxide). Hepatocyte binuclei (red arrow), Nucleolus (yellow arrow), cytoplasm (green arrow), Biliary canaliculus (red arrow head) were clearly visible. White arrows shows the hole formation in cell monolayers, and white arrow head shows the poorly defined intercellular borders

Figure 2: Morphological changes induced by chlorpyrifos at 50 (b), 75 (c) and 150 (d) μM concentrations in rat hepatocytes primary culture compared to control (a) hepatocytes (dimethyl sulfoxide). Hepatocyte binuclei (red arrow), Nucleolus (yellow arrow), cytoplasm (green arrow), Biliary canaliculus (red arrow head) were clearly visible. White arrows shows the hole formation in cell monolayers, and white arrow head shows the poorly defined intercellular borders