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  Indian J Med Microbiol
 

Figure 6: Effects of Amex administered after middle cerebral artery occlusion on protein (a) and mRNA (b) expression of Aquaporin-4 in the brains of middle cerebral artery occlusion-injured mice. Amex was found to significantly suppress Aquaporin-4 overexpression. Representative Western blots and quantitative analysis of Aquaporin-4 protein expression (a) demonstrating the suppressive effect of Amex in brain tissue. Reverse transcription polymerase chain reaction showed that Aquaporin-4 mRNA expression was also suppressed (b). Results are presented as mean ± standard deviations. ###P < 0.001 versus normal group, **P < 0.01, ***P < 0.001 versus control group; n = 6 per group

Figure 6: Effects of Amex administered after middle cerebral artery occlusion on protein (a) and mRNA (b) expression of Aquaporin-4 in the brains of middle cerebral artery occlusion-injured mice. Amex was found to significantly suppress Aquaporin-4 overexpression. Representative Western blots and quantitative analysis of Aquaporin-4 protein expression (a) demonstrating the suppressive effect of Amex in brain tissue. Reverse transcription polymerase chain reaction showed that Aquaporin-4 mRNA expression was also suppressed (b). Results are presented as mean ± standard deviations. <sup>###</sup><i>P</i> < 0.001 versus normal group, **<i>P</i> < 0.01, ***<i>P</i> < 0.001 versus control group; <i>n</i> = 6 per group