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  Indian J Med Microbiol
 

Figure 3: Histological photographs (H and E, 40) of rat liver cells (scale bar, 50 μm). Liver sections of control rat show normal architecture, whereas T4-induced cells present necrosis around the central vein (arrow) and severe inflammation. While no change in ethyl acetate Piper betle- treated rat liver is observed, T4-induced ethyl acetate Piper betle- treated rat shows marked decrease in necrotic and degenerative changes, milder inflammation, and protection from centrilobular necrosis. Liver sections of the animals administered with propylthiouracil in T4 induced show only moderate degree of liver damage

Figure 3: Histological photographs (H and E, 40) of rat liver cells (scale bar, 50 μm). Liver sections of control rat show normal architecture, whereas T<sub>4</sub>-induced cells present necrosis around the central vein (arrow) and severe inflammation. While no change in ethyl acetate <i>Piper betle-</i> treated rat liver is observed, T<sub>4</sub>-induced ethyl acetate <i>Piper betle-</i> treated rat shows marked decrease in necrotic and degenerative changes, milder inflammation, and protection from centrilobular necrosis. Liver sections of the animals administered with propylthiouracil in T<sub>4</sub> induced show only moderate degree of liver damage