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  Indian J Med Microbiol
 

Figure 5: Effect of berberine on neuronal PAS domain protein/brain-derived neurotrophic factor signaling expression of CSDS mice. Protein (a) and Relative mRNA levels (b) of neuronal PAS domain protein 4 in chronic social defeat stress mice hippocampus tissue. Protein (c) and relative mRNA levels (d) of brain-derived neurotrophic factor in chronic social defeat stress mice hippocampus tissue. n = 8 per group; #P < 0.05, ##P < 0.01 versus control, *P < 0.05 versus chronic social defeat stress by analysis of variance followed by Bonferroni's post hoc test. Data are expressed as means ± standard error of the mean

Figure 5: Effect of berberine on neuronal PAS domain protein/brain-derived neurotrophic factor signaling expression of CSDS mice. Protein (a) and Relative mRNA levels (b) of neuronal PAS domain protein 4 in chronic social defeat stress mice hippocampus tissue. Protein (c) and relative mRNA levels (d) of brain-derived neurotrophic factor in chronic social defeat stress mice hippocampus tissue. <i>n</i> = 8 per group; <sup>#</sup><i>P</i> < 0.05, <sup>##</sup><i>P</i> < 0.01 versus control, *<i>P</i> < 0.05 versus chronic social defeat stress by analysis of variance followed by Bonferroni's <i>post hoc</i> test. Data are expressed as means ± standard error of the mean