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  Indian J Med Microbiol
 

Figure 4: Rubus sanctus Schreb. root extract mediated apoptosis of (a) LoVo and (b) HT-29 cell lines. After 24-h treatment with 25%, 50%, and maximum growth inhibition concentrations of Rubus sanctus Schreb. root extract, apoptosis was assessed using the Muse™ Cell Analyzer and the Muse™ Multi-caspase Kit. Hydrogen peroxide (10 mM, 3 h) were used as positive control. Representative multi-caspase profiles (dot plots) are presented. The percentage of total caspase-induced cells (right quadrants) was calculated and shown in the bar graphs. ****P ≤ 0.0001, ***P ≤ 0.0013

Figure 4: <i>Rubus sanctus</i> Schreb. root extract mediated apoptosis of (a) LoVo and (b) HT-29 cell lines. After 24-h treatment with 25%, 50%, and maximum growth inhibition concentrations of <i>Rubus sanctus</i> Schreb. root extract, apoptosis was assessed using the Muse™ Cell Analyzer and the Muse™ Multi-caspase Kit. Hydrogen peroxide (10 mM, 3 h) were used as positive control. Representative multi-caspase profiles (dot plots) are presented. The percentage of total caspase-induced cells (right quadrants) was calculated and shown in the bar graphs. ****<i>P</i> ≤ 0.0001, ***<i>P</i> ≤ 0.0013