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  Indian J Med Microbiol
 

Figure 3: The effect of OB on COX-2, VEGF, p-Akt, PI3K, and PTEN mRNA expression in SMMC-7721 cells. mRNA expression levels of COX-2, VEGF, PI3K, p-Akt, and PTEN in SMMC-7721 cells following OB treatment for 48 h. The mRNA levels of mRNAs were detected by real-time PCR and measured using Piko Real Software with β-actin as an internal reference. All data, repeated by three independent experiments, are presented as mean ± standard deviation. *P < 0.05 and **P < 0.01 versus control group. (a) The expression of COX-2, VEGF, PI3K, p-Akt, and PTEN mRNA in SMMC-7721 cells. (b) Expression of COX-2 in each group. (c )Expression of VEGF in each group. (d) Expression of p-AKT in each group. (e )Expression of PI3K in each group. (f ) Expression of PTEN in each group. VEGF: Vascular endothelial growth factor; PI3K: Phosphatidylinositol-3-kinase; OB: Oroxin B

Figure 3: The effect of OB on COX-2, VEGF, p-Akt, PI3K, and PTEN mRNA expression in SMMC-7721 cells. mRNA expression levels of COX-2, VEGF, PI3K, p-Akt, and PTEN in SMMC-7721 cells following OB treatment for 48 h. The mRNA levels of mRNAs were detected by real-time PCR and measured using Piko Real Software with β-actin as an internal reference. All data, repeated by three independent experiments, are presented as mean ± standard deviation. *<i>P</i> < 0.05 and **<i>P</i> < 0.01 versus control group. (a) The expression of COX-2, VEGF, PI3K, p-Akt, and PTEN mRNA in SMMC-7721 cells. (b) Expression of COX-2 in each group. (c )Expression of VEGF in each group. (d) Expression of p-AKT in each group. (e )Expression of PI3K in each group. (f ) Expression of PTEN in each group. VEGF: Vascular endothelial growth factor; PI3K: Phosphatidylinositol-3-kinase; OB: Oroxin B