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  Indian J Med Microbiol
 

Figure 2: Rhynchophylline prevents ketamine-induced conditioned place preference. (a) The schematic of experimental design for conditioned place preference testing. (b-e) Representative running trajectory of rats in the conditioned place preference compartments recorded and analyzed with the Noldus Ethovision XT 8.5 software; b-e represent the control conditioned place preference group, ketamine conditioned place preference group, ketamine with 30 mg/kg rhynchophylline group and ketamine with 60 mg/kg rhynchophylline group, respectively. (f) Time difference between post ketamine training and pre-ketamine training. Data are expressed as mean values ± standard error of the mean for 8 rats per group. **P < 0.01 versus the control conditioned place preference group; #P < 0.05, ##P < 0.01 versus the ketamine conditioned place preference group via Bonferroni post hoc analysis after one-way analysis of variance

Figure 2: Rhynchophylline prevents ketamine-induced conditioned place preference. (a) The schematic of experimental design for conditioned place preference testing. (b-e) Representative running trajectory of rats in the conditioned place preference compartments recorded and analyzed with the Noldus Ethovision XT 8.5 software; b-e represent the control conditioned place preference group, ketamine conditioned place preference group, ketamine with 30 mg/kg rhynchophylline group and ketamine with 60 mg/kg rhynchophylline group, respectively. (f) Time difference between post ketamine training and pre-ketamine training. Data are expressed as mean values ± standard error of the mean for 8 rats per group. **<i>P</i> < 0.01 versus the control conditioned place preference group; <sup>#</sup><i>P</i> < 0.05, <sup>##</sup><i>P</i> < 0.01 versus the ketamine conditioned place preference group via Bonferroni <i>post hoc</i> analysis after one-way analysis of variance