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  Indian J Med Microbiol
 

Figure 5: Traumatic brain injury induced activation of extracellular signal-regulated kinase. To attenuate the edema, rhubarb significantly inhibited the extracellular signal-regulated kinase signaling pathway to downregulate matrix metalloproteinase 9 and upregulate zonula occluden-1

Figure 5: Traumatic brain injury induced activation of extracellular signal-regulated kinase. To attenuate the edema, rhubarb significantly inhibited the extracellular signal-regulated kinase signaling pathway to downregulate matrix metalloproteinase 9 and upregulate zonula occluden-1