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  Indian J Med Microbiol
 

Figure 7: Effect of 20-hydroxyecdysone, momordin Ic, and oleanolic acid from K. scoparia on LPS-stimulated PGE2 production in RAW 264.7 cells. The production of PGE2 was measured in culture medium of cells pretreated with various concentrations (6.25, 12.5, or 25 μM) of 20-hydroxyecdysone, momordin Ic, or oleanolic acid for 4 h and then stimulated with LPS (1 μg/mL) for 20 h. Indomethacin (2.5 ng/mL) were used as positive control. Each bar represents the mean of three independent experiments. ##P < 0.01 vs. untreated control; *P < 0.05 and **P < 0.01 vs. LPS-treated cells

Figure 7: Effect of 20-hydroxyecdysone, momordin Ic, and oleanolic acid from <i>K. scoparia</i> on LPS-stimulated PGE<sub>2</sub> production in RAW 264.7 cells. The production of PGE2 was measured in culture medium of cells pretreated with various concentrations (6.25, 12.5, or 25 μM) of 20-hydroxyecdysone, momordin Ic, or oleanolic acid for 4 h and then stimulated with LPS (1 μg/mL) for 20 h. Indomethacin (2.5 ng/mL) were used as positive control. Each bar represents the mean of three independent experiments. <sup>##</sup><i>P</i> < 0.01 vs. untreated control; *<i>P</i> < 0.05 and **<i>P</i> < 0.01 vs. LPS-treated cells