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  Indian J Med Microbiol
 

Figure 4: Effects of herbal extracts on [3H5α-DHT binding to the AR in COS-7 cells. (A) Trichosanthes kirilowii (TK), (B) Asarum sieboldii (AS), (C) Sanguisorba officinalis (SO) and (D) Xanthium strumarium (XS). AR-binding inhibition was determined in COS-7 cells transiently transfected with pCMV-AR as described in the methodology above. Results are expressed as the percentage of binding relative to [3]H 5α-DHT alone and are shown for unlabeled herbal extracts. Data are expressed as the means ± SD from three independent experiments.*p < 0.05 and **p< 0.01 vs. untreated control

Figure 4: Effects of herbal extracts on [<sup>3</sup>H5<i>α</i>-DHT binding to the AR in COS-7 cells. (A) <i>Trichosanthes kirilowii</i> (TK), (B) <i>Asarum sieboldii</i> (AS), (C) <i>Sanguisorba officinalis</i> (SO) and (D) <i>Xanthium strumarium</i> (XS). AR-binding inhibition was determined in COS-7 cells transiently transfected with pCMV-AR as described in the methodology above. Results are expressed as the percentage of binding relative to <sup>[3]</sup>H 5<i>α</i>-DHT alone and are shown for unlabeled herbal extracts. Data are expressed as the means ± SD from three independent experiments.<sup>*</sup><i>p</i> < 0.05 and <sup>**</sup><i>p</i>< 0.01 vs. untreated control