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  Indian J Med Microbiol
 

Figure 4: Effects of an external Ca2+-free solution and of thapsigargin on daikenchuto-induced pacemaker potential depolarization in cultured interstitial cells of Cajal from mouse small intestine. (a) External Ca2+-free solution and (b) thapsigargin (5 μM) abolished the generation of pacemaker potentials and blocked daikenchuto-induced pacemaker potential depolarization. (c) Responses to daikenchuto in external Ca2+-free solution and in the presence of thapsigargin are summarized. Bars represent mean ± standard error of the means. **P < 0.01. Significantly different from nontreated controls. CTRL: ControlThapsi: Thapsigargin

Figure 4: Effects of an external Ca<sup>2+</sup>-free solution and of thapsigargin on daikenchuto-induced pacemaker potential depolarization in cultured interstitial cells of Cajal from mouse small intestine. (a) External Ca<sup>2+</sup>-free solution and (b) thapsigargin (5 μM) abolished the generation of pacemaker potentials and blocked daikenchuto-induced pacemaker potential depolarization. (c) Responses to daikenchuto in external Ca<sup>2+</sup>-free solution and in the presence of thapsigargin are summarized. Bars represent mean ± standard error of the means. **<i>P</i> < 0.01. Significantly different from nontreated controls. CTRL: ControlThapsi: Thapsigargin