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  Indian J Med Microbiol
 

Figure 5: (a-c) Effects of gallic acid, ellagic acid, and quercetin from radix Sanguisorbae on lipopolysaccharide-stimulated prostaglandin E2 production in RAW 264.7 cells. Prostaglandin E2 production was measured in the culture medium of cells that had been pretreated with various concentrations (6.25, 12.5, or 25 µM) of each compound for 4 h and then stimulated with lipopolysaccharide (1 µg/mL) for 20 h. Indomethacin (1.25 ng/mL) was used as the positive control. Each bar represents the mean of three independent experiments. ##P < 0.01 versus untreated control; and *P < 0.05 and **P < 0.01 versus lipopolysaccharide-treated cells

Figure 5: (a-c) Effects of gallic acid, ellagic acid, and quercetin from radix Sanguisorbae on lipopolysaccharide-stimulated prostaglandin E2 production in RAW 264.7 cells. Prostaglandin E2 production was measured in the culture medium of cells that had been pretreated with various concentrations (6.25, 12.5, or 25 µM) of each compound for 4 h and then stimulated with lipopolysaccharide (1 µg/mL) for 20 h. Indomethacin (1.25 ng/mL) was used as the positive control. Each bar represents the mean of three independent experiments. <sup>##</sup><i>P</i> < 0.01 versus untreated control; and *<i>P</i> < 0.05 and **<i>P</i> < 0.01 versus lipopolysaccharide-treated cells