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  Indian J Med Microbiol
 

Figure 3: (a-c) Effect of gallic acid, ellagic acid, and quercetin from radix Sanguisorbae on lipopolysaccharide-stimulated TNF-α production in RAW 264.7 cells. TNF-α production was measured in the culture medium of cells that had been pretreated with various concentrations (6.25, 12.5, or 25 µM) of each compound for 4 h and then stimulated with lipopolysaccharide (1 µg/mL) for 20 h. Each bar represents the mean of three independent experiments. ##P < 0.01 versus untreated control, and *P < 0.05 and **P < 0.01 versus lipopolysaccharide-treated cells

Figure 3: (a-c) Effect of gallic acid, ellagic acid, and quercetin from radix Sanguisorbae on lipopolysaccharide-stimulated TNF-α production in RAW 264.7 cells. TNF-α production was measured in the culture medium of cells that had been pretreated with various concentrations (6.25, 12.5, or 25 µM) of each compound for 4 h and then stimulated with lipopolysaccharide (1 µg/mL) for 20 h. Each bar represents the mean of three independent experiments. <sup>##</sup><i>P</i> < 0.01 versus untreated control, and *<i>P</i> < 0.05 and **<i>P</i> < 0.01 versus lipopolysaccharide-treated cells