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  Indian J Med Microbiol
 

Figure 4: (a) Xanthohumol induces DNA fragmentation. Percentage of cells in R1 region represents cells with DNA fragmentation. (b) Statistical significance to control is marked with ** (P * 0.01). (c) Cell cycle progression. The percentage of apoptotic cells at hypodiploid DNA peak (sub-G1 population, blue peak) and percentage of cells accumulated at S phase increased at higher concentrations. (d) Percentage of cells at various cell cycle phases. Statistical significance to control is marked with (*) (P < 0.05) and (**) (P < 0.01)

Figure 4: (a) Xanthohumol induces DNA fragmentation. Percentage of cells in R1 region represents cells with DNA fragmentation. (b) Statistical significance to control is marked with ** (<i>P</i> * 0.01). (c) Cell cycle progression. The percentage of apoptotic cells at hypodiploid DNA peak (sub-G1 population, blue peak) and percentage of cells accumulated at S phase increased at higher concentrations. (d) Percentage of cells at various cell cycle phases. Statistical significance to control is marked with (*) (<i>P</i> < 0.05) and (**) (<i>P</i> < 0.01)