Pharmacognosy Magazine

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 10  |  Issue : 39  |  Page : 304--313

Analysis of the influence of sulfur-fumigation on the volatile components of Angelicae sinensis Radix by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry


Gang Cao1, Hao Cai2, Yajing Lou3, Sicong Tu4, Xiao Liu2, Kunming Qin3, Baochang Cai1 
1 Department of Chinese Materia Medica, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing; Research Center of TCM Processing Technology, Zhejiang Chinese Medical University, Hangzhou; National First-Class Key Discipline for Science of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, P. R. China
2 Department of Chinese Materia Medica, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing; National First-Class Key Discipline for Science of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, P. R. China
3 Department of Chinese Materia Medica, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
4 Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia

Correspondence Address:
Hao Cai
Department of Chinese Materia Medica, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, P. R. China

Background: Sulfur-fumigation of Angelicae sinensis Radix causes changes in the structure and composition of volatile components. These changes alter the curative effect and the quality of A. sinensis Radix. Materials and Methods: In this study, comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GC × GC-TOFMS) was employed to investigate the influence of sulfur-fumigation on the volatile components, and to characterize and quantify the chemical composition of the volatile oil of A. sinensis Radix. Results: The present study has shown that sulfur-fumigated A. sinensis Radix samples had significant loss of the main active compounds and a more destructive fingerprint profile compared to non-fumigated samples. Conclusion: From this study, it can be concluded that the combination of GC × GC and TOFMS has potential as a quality monitoring tool in herbal medicine and food processing industries.


How to cite this article:
Cao G, Cai H, Lou Y, Tu S, Liu X, Qin K, Cai B. Analysis of the influence of sulfur-fumigation on the volatile components of Angelicae sinensis Radix by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry .Phcog Mag 2014;10:304-313


How to cite this URL:
Cao G, Cai H, Lou Y, Tu S, Liu X, Qin K, Cai B. Analysis of the influence of sulfur-fumigation on the volatile components of Angelicae sinensis Radix by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry . Phcog Mag [serial online] 2014 [cited 2021 Sep 26 ];10:304-313
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2014;volume=10;issue=39;spage=304;epage=313;aulast=Cao;type=0