Pharmacognosy Magazine

SHORT COMMUNICATION
Year
: 2011  |  Volume : 7  |  Issue : 26  |  Page : 157--160

Standardization of spray-dried powder of Piper betle hot water extract


Liyanage Dona Ashanthi Menuka Arawwawala1, Horadugoda Gamage Sujatha Pushpakanthi Hewageegana2, Lakshmi Sriyani Rajapaksha Arambewela1, Hettiarachchige Sami Ariyawansa2 
1 Industrial Technology Institute, Bauddhaloka Mawatha, Colombo 7, Sri Lanka
2 Department of Nidana Chikitsa, Institute of Indigenous Medicine, University of Colombo, Rajagiriya, Sri Lanka

Correspondence Address:
Liyanage Dona Ashanthi Menuka Arawwawala
Industrial Technology Institute, Bauddhaloka Mawatha, Colombo 7
Sri Lanka

The leaves of Piper betle Linn. (Family: Piperaceae) possess several bioactivities and are used in the Traditional Medical systems of Sri Lanka. The present investigation was carried out to standardize the spray-dried powder of P. betle by (a) determination of physicochemical parameters, presence or absence of heavy metals, and microbial contamination; (b) screening for phytochemicals; and (c) development of High Pressure Liquid Chromatography (HPLC) fingerprint and densitogram. The percentages of moisture content, total ash, acid insoluble ash, water-soluble ash, and ethanol extractable matter of spray-dried powder of P. betle were 2.2-2.5, 6.8-7.0, 0.003-0.005, 4.1-4.3, and 15.8-16.2, respectively. The concentrations of all the tested heavy metals were below the WHO acceptable limits and bacterial species, such as Escherichia coli, Salmonella spp, Staphylococcus aureus, and Pseudomonas aeroginosa were not present in the P. betle spray-dried powder. Phenolic compounds, tannins, flavonoids steroids, and alkaloids were found to be present in the spray-dried powder of P. betle and HPLC fingerprint and densitogram clearly demonstrated the proportional differences of these chemical constituents. In conclusion, the results obtained from this study can be used to standardize the spray-dried powder of P. betle.


How to cite this article:
Arawwawala LA, Hewageegana HS, Arambewela LR, Ariyawansa HS. Standardization of spray-dried powder of Piper betle hot water extract.Phcog Mag 2011;7:157-160


How to cite this URL:
Arawwawala LA, Hewageegana HS, Arambewela LR, Ariyawansa HS. Standardization of spray-dried powder of Piper betle hot water extract. Phcog Mag [serial online] 2011 [cited 2021 Apr 21 ];7:157-160
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2011;volume=7;issue=26;spage=157;epage=160;aulast=Arawwawala;type=0