Pharmacognosy Magazine

RESEARCH ARTICLE
Year
: 2009  |  Volume : 5  |  Issue : 20  |  Page : 324--328

Cytotoxic and Antibacterial Constituents from the Roots of Sonchus oleraceus L. Growing in Egypt


Ehab Saad Elkhayat 
 Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut branch, Assiut 71524, Egypt

Correspondence Address:
Ehab Saad Elkhayat
Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut branch, Assiut 71524
Egypt

Phytochemical study of the roots of Sonchus oleraceus L. (Astraceae) Growing in Egypt, afforded loliolide 1 for the first time from the genus Sonchus in addition to 15-O- β -glucopyranosyl-11 β ,13-dihydrourospermal A 2 , ursolic acid 3 , lupeol 4 and β-sitosterol- 3-O-glucopyranoside 5 for the fi rst time from the plant. The biological evaluation of the isolated compounds showed cytotoxic activity of 1 and 2 against PC33 and L5187Y cell lines, in addition to antibacterial activity against S.aureus , B. subtilis , E. Coli and N. gohnorea . The structures of the compounds were elucidated using 1D ( 1 H and 13C), 2D (H-H COSY, H S QC and HMBC) NMR and MS spectroscopic data.


How to cite this article:
Elkhayat ES. Cytotoxic and Antibacterial Constituents from the Roots of Sonchus oleraceus L. Growing in Egypt.Phcog Mag 2009;5:324-328


How to cite this URL:
Elkhayat ES. Cytotoxic and Antibacterial Constituents from the Roots of Sonchus oleraceus L. Growing in Egypt. Phcog Mag [serial online] 2009 [cited 2021 Jun 25 ];5:324-328
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2009;volume=5;issue=20;spage=324;epage=328;aulast=Elkhayat;type=0