Pharmacognosy Magazine

RESEARCH ARTICLE
Year
: 2009  |  Volume : 5  |  Issue : 20  |  Page : 301--305

Hypolipidemic Effects of Seed Extract of Celery (Apium graveolens ) in Rats


Kamal Mansi1, Adel M Abushoffa2, Ahmad Disi3, Talal Aburjai4 
1 Department of Biological Sciences, Faculty of Science, Al al-bayt University, Mafraq, Jordan
2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alfateh University of Medical Sciences, Tripoli, Libya, P.O.Box 13620, Libya
3 Department of Biological Sciences, Faculty of Science, University of Jordan, Amman 11942, Jordan
4 Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman 11942, Jordan

Correspondence Address:
Talal Aburjai
Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman 11942
Jordan

The hypolipidemic effects of ethanol extract of A. graveolens L. (Apiaceae) were investigated. Forty adult male albino rats weighing about 260 g each, were divided into four groups (n = 10). Experimental animals were gavaged at doses of 213 and 425 mg/kg body wt. for sixty consecutive days. Extract showed a significant decrease (p<0.05) of serum total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-c), and significant increase (p<0.05) in high-density lipoprotein cholesterol (HDL-c) in the treated groups. The oral administration of ethanol extract of A. graveolens revealed good hypolipideamic effects in adult male albino rats. The results have given a considerable agreement to the traditional use of A. graveolens in the treatment of hyperlipidemia; it could possibly lead to appropriate changes in blood lipid profiles.


How to cite this article:
Mansi K, Abushoffa AM, Disi A, Aburjai T. Hypolipidemic Effects of Seed Extract of Celery (Apium graveolens ) in Rats.Phcog Mag 2009;5:301-305


How to cite this URL:
Mansi K, Abushoffa AM, Disi A, Aburjai T. Hypolipidemic Effects of Seed Extract of Celery (Apium graveolens ) in Rats. Phcog Mag [serial online] 2009 [cited 2021 May 14 ];5:301-305
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2009;volume=5;issue=20;spage=301;epage=305;aulast=Mansi;type=0