Pharmacognosy Magazine

RESEARCH ARTICLE
Year
: 2009  |  Volume : 5  |  Issue : 19  |  Page : 51--54

Antidiabetic activity of aqueous extract of Eucalyptus citriodorahook. in alloxan induced diabetic rats


Arjun Patra1, Shivesh Jha3, Alakh N Sahu2 
1 College of Pharmacy, IFTM, Moradabad 244 001, U.P; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra 835 215, Ranchi, Jharkhand, India
2 Department of Pharmaceutics, IT, BHU, Varanasi, India

Correspondence Address:
Arjun Patra
College of Pharmacy, IFTM, Moradabad 244 001, U.P; Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra 835 215, Ranchi, Jharkhand
India

The present study was undertaken to study the antidiabetic activity of the aqueous extract of Eucalyptus citriodora Hook. leaf in alloxan-induced diabetic rats. The activity of the extract was studied on glucose loaded and alloxan-induced diabetic rats. In both the tests, the extract has shown significant and considerable antidiabetic effect in a dose dependent manner. On oral administration of the extract at a dose of 500 mg/kg of body weight, the reduction of blood glucose level was 22.9% after 4th hr and on continuous administration the reduction in blood glucose level after 21 days was 49.9 and 56.8% with dose of 250 and 500 mg/kg of body weight respectively. Aqueous extract of leaves of E. citriodora exhibited significant antidiabetic activity which was comparable with the standard drug Glibenclamide.


How to cite this article:
Patra A, Jha S, Sahu AN. Antidiabetic activity of aqueous extract of Eucalyptus citriodorahook. in alloxan induced diabetic rats.Phcog Mag 2009;5:51-54


How to cite this URL:
Patra A, Jha S, Sahu AN. Antidiabetic activity of aqueous extract of Eucalyptus citriodorahook. in alloxan induced diabetic rats. Phcog Mag [serial online] 2009 [cited 2021 Oct 28 ];5:51-54
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2009;volume=5;issue=19;spage=51;epage=54;aulast=Patra;type=0