Pharmacognosy Magazine

RESEARCH ARTICLE
Year
: 2009  |  Volume : 5  |  Issue : 18  |  Page : 122--126

In vitro Antioxidant and Free Radical Scavenging Activity of Diospyros lotus and Pyrus boissieriana growing in Iran


Seyed Mohammad Nabavi1, Mohammad Ali Ebrahimzadeh1, Seyed Fazel Nabavi1, Mojtaba Fazelian1, Bahman Eslami2 
1 Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, 48189, Sari, Iran
2 Department of Biology, Islamic Azad University, Ghaemshahr, Iran

Correspondence Address:
Mohammad Ali Ebrahimzadeh
Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, 48189, Sari
Iran

Current research into free radicals has confirmed that foods rich in antioxidants play an essential role in the prevention of many diseases. The potential antioxidant activities of Diospyros lotus and Pyrus boissieriana fruits investigated employing six in vitro assay systems. IC 50 for DPPH radical-scavenging activity was 1.45 ± 0.03 for D. lotus and 3.0 ± 0.04 mg ml -1 for P. boissieriana, respectively. The extracts showed weak nitric oxide-scavenging and Fe 2* chelating ability activity. The D. lotus extracts was better than P. boissieriana. The peroxidation inhibition of D. lotus and P. boissieriana extracts exhibited values from 89 (at 24 th ) to 94% (at 72 nd hrs) and 91 to 95% respectively. Neither of them showed good scavenging activity of H 2 0 2 . The total amount of phenolic compounds in each extracts was determined as gallic acid equivalents and total flavonoid contents were calculated as quercetin equivalents from a calibration curve. Both of them had high total phenolic and flavonoid contents.


How to cite this article:
Nabavi SM, Ebrahimzadeh MA, Nabavi SF, Fazelian M, Eslami B. In vitro Antioxidant and Free Radical Scavenging Activity of Diospyros lotus and Pyrus boissieriana growing in Iran.Phcog Mag 2009;5:122-126


How to cite this URL:
Nabavi SM, Ebrahimzadeh MA, Nabavi SF, Fazelian M, Eslami B. In vitro Antioxidant and Free Radical Scavenging Activity of Diospyros lotus and Pyrus boissieriana growing in Iran. Phcog Mag [serial online] 2009 [cited 2022 Aug 19 ];5:122-126
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2009;volume=5;issue=18;spage=122;epage=126;aulast=Nabavi;type=0