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Year : 2019  |  Volume : 15  |  Issue : 61  |  Page : 356-361

Photoprotective activity of medicinal plants from the caatinga used as anti-inflammatories

1 Department of Pharmaceutical Sciences, Federal University of Pernambuco, Caruaru, Brazil
2 Nurse Coordination, University Center Valley Ipojuca, Caruaru, Brazil
3 Department of Pharmaceutical Sciences, Federal University of Pernambuco, Caruaru; Department of Health, University Center Mauricio de Nassau, Recife, Brazil
4 Department of Health, University Center Mauricio de Nassau, Recife, Brazil

Correspondence Address:
Bruno de Almeida Andrade
Departament of Pharmaceutical Sciences, Federal University of Pernambuco, Street Arthur Sá, Recife
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/pm.pm_482_18

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Background: Exposure to ultraviolet (UV) radiation may cause photoaging, unsightly marks, or dangerous lesions, such as carcinomas and/or melanomas. Sun filters are substances capable of absorbing, reflecting, or refracting UV radiation and thus protect the skin from direct exposure to sunlight. The current trend in the cosmetics industry, in Brazil, is to rationally explore local biodiversity as a way of developing products of natural origin, especially derived from plants. Objective: The present study aims to determine the in vitro sun protection factor (SPF) of 15 species from the Caatinga region used in popular medicine as anti-inflammatories. Materials and Methods: Samples of duly identified plant species were dried and ground and hydroethanolic extracts were obtained (80:20). Spectrophotometric analyses were carried out to determine the SPF, antioxidant activity, and quantification of secondary metabolites. In vitro calculation of SPF was based on the method developed by Mansur. Results: Erythrina velutina Willd. had the best SPF of 9.71 ± 1.29 at a concentration of 100 mg/L. Conclusion: The study showed that native species to the Caatinga used by the local population to treat inflammatory disorders have good photoprotective potential and could be used for pharmaceutical preparations to this end. Abbreviations used: ANOVA: Analysis of variance; AOA: Antioxidant activity; CC: Coumarin content; CE: Coumarin equivalent; DNA: Deoxyribonucleic acid; DPPH: 2,2-diphenyl-1-picrylhydrazyl; IC50: Inhibitory concentration 50%; LEA-UFPE: Laboratory of Ecology and Evolution of Social-ecological Systems-Federal University of Pernambuco; RE: Rutin equivalent; SPF: Sun protection factor; TAE: Tannic acid equivalent; TFC: Total flavonoid content; TPC: Total phenolic content; TTC: Total tannin content; UFPE: Federal University of Pernambuco; UFRPE: Federal Rural University of Pernambuco; UV: Ultraviolet; UVA: Ultraviolet type A; UVB: Ultraviolet type B; UV-VIS: Ultraviolet-visible

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