|Year : 2019 | Volume
| Issue : 60 | Page : 115-123
An ethnobotanical and ethnomedicinal survey of traditionally used medicinal plants in Seymour, South Africa: An attempt toward digitization and preservation of ethnic knowledge
Lisa Valencia Buwa-Komoren1, Buyisile Mayekiso2, Zoleka Mhinana2, Ariyo Lateef Adeniran3
1 Department of Plant Sciences, Faculty of Natural and Agricultural Sciences, University of the Free State, Phuthaditjhaba, South Africa
2 Department of Botany, University of Fort Hare, Alice, South Africa
3 Department of Biochemistry and Physiology, Faculty of Veterinary Medicine, University of Abuja, Abuja, Nigeria
|Date of Submission||16-May-2018|
|Date of Decision||08-Jun-2018|
|Date of Web Publication||23-Jan-2019|
Lisa Valencia Buwa-Komoren
Department of Plant Sciences, Faculty of Natural and Agricultural Sciences, University of The Free State, Private Bag X13, Phuthaditjhaba 9866
Source of Support: None, Conflict of Interest: None
| Abstract|| |
Introduction: Medicinal plants have been used for the treatment of both infectious and noninfectious diseases by the majority of the world's population for many years. The low socioeconomic standing of Eastern Cape population suggests that the majority of people use traditional methods of health care. Many of the rural communities in this province have no access to Western medical health care and rely on traditional medicine for their primary health-care needs. Materials and Methods: An ethnobotanical survey was conducted from February 2013 to December 2015 to investigate the use of medicinal plants by the people of Seymour in the Eastern Cape Province of South Africa. Information was gathered from nine traditional healers, seven herbalists, and 18 elderly villagers. Results: The information collected revealed six ailment categories that were treated with a wide range of medicinal plants. A total of 50 plant species belonging to 29 families were reported to be used in the treatment of various ailments. Members of the family Asteraceae, Euphorbiaceae, Fabaceae, and Rutaceae had the highest number of species used in traditional healing. Leaves were reported to be the most frequently used plant part, followed by roots, bark, stem, and then corms and rhizomes. The survey indicated that the most prominent method of herbal administration used is orally via extracts that were obtained by boiling, either as a decoction or concoction. Conclusions: This study has documented important information on medicinal plants used by people, traditional healers, and herbalists of Seymour region in the Eastern Cape Province of South Africa to treat various ailments.
Abbreviations used: ACE: Angiotensin-converting enzyme; CNS: Central nervous system; ENT: Ear, nose and throat; HIV: Human Immunodeficiency virus; ICF: Informant consensus factor; Nur: Total number of use report; Nt: Number of taxa; TB: Tuberculosis
Keywords: Ailments, ethnobotanical survey, herbalists, medicinal plants, traditional healers
|How to cite this article:|
Buwa-Komoren LV, Mayekiso B, Mhinana Z, Adeniran AL. An ethnobotanical and ethnomedicinal survey of traditionally used medicinal plants in Seymour, South Africa: An attempt toward digitization and preservation of ethnic knowledge. Phcog Mag 2019;15:115-23
|How to cite this URL:|
Buwa-Komoren LV, Mayekiso B, Mhinana Z, Adeniran AL. An ethnobotanical and ethnomedicinal survey of traditionally used medicinal plants in Seymour, South Africa: An attempt toward digitization and preservation of ethnic knowledge. Phcog Mag [serial online] 2019 [cited 2022 Aug 12];15:115-23. Available from: http://www.phcog.com/text.asp?2019/15/60/115/250599
- Medicinal plants have been used for ages in the treatment and management of various diseases but many of these plants have been poorly described. In order to optimise the use of these plants, there is a need for proper documentation of the indigenous knowledge that will attract different researchers to scientifically validate and do further exploration of these plants in the development of drugs.
| Introduction|| |
Plants have been used as drugs for centuries, initially as traditional preparations. It is estimated that about 85% of traditional medicines used for primary health care globally are derived from plants. Even with conventional or orthodox medicine available, most people, especially from rural areas, still prefer using traditional medicine to treat most ailments. The World Health Organization estimated that 80% of the developing world population use traditional medicine. In Africa alone, it is estimated that 70%–80% of people still prefer consulting traditional medical practitioners for health care.,
In South Africa, like in other African countries, traditional medicine has a very deep-rooted and rich cultural heritage., An estimate of about 3000 plant species are used by approximately 200,000 traditional healers in this country. More than 60% of South Africans consult these traditional healers for their health-care needs and cultural practices on a regular basis., The Eastern Cape Province of South Africa has high plant species richness, and the low socio-economic standing of this large, predominantly rural province suggests that the majority of people use traditional methods of health care., Conventional medicines, although helpful, are not easily accessible to many people in rural communities where there is limited access to medical facilities as well as increasing rates of unemployment and rising medical costs.
In South Africa, there is great cultural diversity and several ethnic groups. This has resulted in massive use of medicinal plants throughout the provinces. Each cultural group has different medicinal solutions for the management of same diseases.,, The Seymour area of the Eastern Cape Province is made up of the Xhosa tribes of South Africa and embedded with a strong tradition of using medicinal plants to cure different diseases.
Few researchers have conducted different researches in Eastern Cape Province including survey-based methodology, but mostly focus on single ailment such as diarrhea; reproductive system diseases; mental illness; respiratory infections; skin ailments; and ear, nose, and throat (ENT) infections.,,,,, There is, however, a need to collect more data from the knowledge holders of their use of diverse plants in the management of different kinds of diseases. These undisclosed ethnobotanical data are important to be collected and urgently documented as the traditional knowledge about plants and their medicinal use is fast disappearing due to socioeconomic change, land use, climate change, and plant overexploitation.
Ethnobotanical studies encourage the continuous search for natural products for use as medicines. Ethnobotanical surveys have been found to be one of the reliable approaches of discovering new drugs and new drug development. The decline on the knowledge of medicinal plant usage is a concern in Africa. This decline is due to the fact that this significant knowledge is often transmitted from the older generation to the younger via word of mouth and most of it has not been documented. This is worsened by the increase of Western lifestyle among communities and the lack of interest of the younger generation to carry on the tradition, which leads to the reduction in the number of traditional healers. Therefore, to protect our ancestral knowledge of medicinal plants from completely being lost, we need to record it. One of the best modern approaches to the preservation of traditional knowledge is documentation in some permanent form and public accessibility. Documentation and digitization of traditional medicine knowledge is the surest means of preservation; it ensures preservation of the delicate knowledge and ensures wider dissemination. It will also result in codification of best practices which can be transmitted across communities in developing countries. It is an effective tool for defensive protection from biopiracy as well as expropriation without compensation by multinational pharmaceutical companies. It is a veritable tool for checking any attempt by multinational corporations to privatize such knowledge via Intellectual Property Right mechanisms such as patent. Hence, when considering the patentability of any claimed subject matter, availability of traditional medicine knowledge database enables patent examiners all over the world to effectively and efficiently evaluate the novelty of the claim.
The majority of the inhabitants of Seymour in the most rural areas rely on traditional medicine for their health-care problems, and there is no documented information about the traditional medicinal plants and associated indigenous uses in the area. Accordingly, this article was aimed at collecting, documenting, and digitalizing the information for future referencing.
| Materials and Methods|| |
The study was conducted among elderly villagers, traditional healers, and herbalists in four villages (Phakamisa, Old location, Izinyoka, and Joza) of Seymour. Seymour is a poor undeveloped rural area located between latitude 32°37′ 18″ S and longitude 26°48′ 48″ E in the Eastern Cape Province of South Africa. The altitude is approximately 1300 m above the sea level and the vegetation is Veld type 7. The ethnic group in this area is Xhosa speaking.
Data were collected between February 2013 and December 2015. Following the methods of Jovel et al., information was compiled through general conversations with the informants, while structured questionnaires [Table 1] were used to obtain additional information about the methods of treatment. The information that was recorded included local names of the plants used, their local uses, parts of the plants used, the mode of preparation and forms of administration of the medicinal plants, age group, and gender of the persons interviewed.
A total of 34 informants, comprising nine traditional healers, seven herbalists, and 18 elderly villagers were interviewed. Eighteen of the interviewees were male and were between the ages of 39 and 70 years, while the remaining 16 were female whose ages ranged between 35 and 67 years. [Figure 1] shows a female traditional healer being consulted by one of the inhabitants of Seymour. All the interviewees orally consented, without any financial compensation, to share their knowledge with us for the purpose of the study. Arranging the interviews was not a hassle as the researchers are familiar with the location and its residents.
Informants offered to collect plant specimens they use and those they know to be of medicinal value in the area. They accompanied the researchers to the field to identify the various plant species which were not growing or cultivated near their homes. In the process, plant specimens concerned were collected. The plants were initially identified by their common names (Xhosa) and later validated at Giffen Herbarium at the University of Fort Hare. Voucher specimens (Makinana 01–50) were prepared and deposited at the Giffen Herbarium.
Quantitative indices such as informant consensus factor (ICF) were calculated on Microsoft Excel 2013 spreadsheet and GraphPad Prism software version 5 (GraphPad Software, Carlifonia, USA).
Informant consensus factor
ICF was calculated thus as follows: (Nur – Nt)/(Nur – 1).
Where Nur= Total number of use report for each ailment category: Nt= Number of taxa used in the category.
| Results and Discussion|| |
The survey established that people of Seymour are still making use of medicinal plants. The gathered information was processed and analyzed in order to get the data in these aspects. A total of 34 informants, comprising nine traditional healers (26%), seven herbalists (21%), and 18 elderly villagers (52%) were interviewed. Eighteen of the interviewees comprised 52% of males and 48% of females. Their respective age range was 39–70 years and 35–67 years for the male and female respondents. In the Eastern Cape Province, the care of family is a shared responsibility between the father and mother, hence the observed equal representation of gender involved in the knowledge of different recipes that can be used to manage different ailments and take care of the family. This result is consistent with other surveys with similar societal belief., The results obtained from this survey [Table 2] indicated that 50 plant species belonging to 29 families were used in the treatment of various ailments by the people of Seymour. The results from the study also showed that members of the family Asteraceae (six species) were the most commonly used plants in this area, followed by Euphorbiaceae (four species), Fabaceae (four species), Rutaceae (four species), Apiaceae (three species), Alliaceae (two species), Amaryllidaceae (two species), Asclepiadaceae (two species), Polygonaceae (two species), and Solanaceae (two species), while the remaining 19 families had one species each.
|Table 2: List of medicinal plants used for the treatment of various ailments common in the Seymour region of the Eastern Cape Province|
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In this survey, nine ailment categories were frequently mentioned and are treated with a wide range of medicinal plants. These are respiratory system diseases; reproductive system diseases; musculoskeletal disorder; gastrointestinal diseases; ulcer, wound, and sores; ENT problems; fever; infectious diseases; and circulatory system diseases which are documented in [Table 3]. Twenty-three species belonging to 18 families were reported for the treatment of these ailments, with members of the families Asteraceae (three species) and Rutaceae (three species) as the most commonly used. Respiratory system diseases included shortness of breath, asthma, and bronchitis, which had the highest ICF value of 0.65 followed by reproductive system diseases and musculoskeletal system of 0.60 and 0.57, respectively [Table 3]. The higher ICF values observed could be due to the ability of the respondents to easily diagnose and treat with the available medicinal plants. Studies undertaken in Morocco and Turkey agree with our finding that respiratory system diseases had the highest ICF values., Reports on pharmacological activities of Asteraceae and Rutaceae included inhibition of rotavirus, antileishmanial, antidiabetic, antioxidant, antimycobacterial, antimalarial, antibacterial, and antifungal activities.,,,, Aloe ferox, Alepidia amatymbica, Arctotis arctotoides, Taraxacum officinale, Strychnos henningsii and Tulbaghia violacea were reported to be used in the treatment of digestive system disorders, which included indigestion, constipation, stomach aches, diarrhea, and vomiting. Twenty-one species in 15 families were mentioned to be used in this category, with members of families Asteraceae (three species), Fabaceae (two species), Polygonaceae (two species), Asclepiadaceae (two species), and Euphorbiaceae (two species) as the most commonly used. Gynecological problems included infertility, dysmenorrhea, and menorrhagia. Nine plant species were reported to be effective in treating these ailments. The wounds' category included severe wounds, cuts, ulcers, sores, rashes, and warts. Seven species in six families were reportedly sought for their effective medicinal curative properties in this category. Six species including Helychrisum odoratissimum, Ricinus communis, and Leonotis leonurus were reported to be used for headaches. Most of the plant species discovered in this survey were used to treat more than one ailments. For example, Strychnos henningsii was reported to be used in the treatment of tuberculosis (TB), dysmenorrhea, constipation, and rheumatism. Pharmacological activities reported for Euphorbiaceae families included antidepressant, aphrodisiac, antidiarrheal, antibacterial, anthelmintic, deticking, and antimalarial properties and depression of central nervous system (CNS),,, while Fabaceae properties included antimicrobial, antidiabetic, cardioprotective, antiviral, anti-inflammatory, anticancer, antihypertensive, and antiparasitic.,, Medicinal plants from Apiaceae, Polygonaceae, and Solanaceae families were reported by researchers to possess numerous pharmacological activities, including CNS effect, antioxidant, antipyretic, antiathric, anti-inflammatory, antimicrobial, antidiarrheal, anticancer and angiotensin-converting enzyme (ACE) inhibitory activities, and effectiveness on serotonin reuptake transport protein.,,,,
Leaves were reported to be the most commonly used part of the plants (22%) as depicted in [Figure 2]. This was followed by roots, bulbs, corms, and rhizomes, and then bark and stem. Fruits were reported as the least used part of the plants. The level of consumption of these parts for medicinal purpose may be due to the presence of active metabolites present in them. The leaves is the center of biosynthesis of different metabolites, which may contain many bioactive principles that have good medicinal properties.,, Different methods of herbal preparation were also mentioned during the interview process. Preparing decoction and infusion from the plant material was the most commonly used method of preparation [Figure 3]. Grinding the plant material into fine powder was the preparatory method often used in the treatment of headaches, blocked nose, and other nose infections as well as respiratory ailments, while boiling the leaf making a warm brew was mainly used in the treatment of ear aches. Grinding plant material into fine powder and making a paste was often used in the treatment of wounds and skin infections. Heating the leaf and cut open fresh stem, burning the plant material into ashes, and making a paste were other reported preparatory methods used for the treatment of wounds. Using the fresh material as it is, with no preparations, was another method used in the treatment of coughs, colds, and blocked nose.
|Figure 2: The different parts of plants used against ailments common among the residents of Seymour area in the Eastern Cape Province, South Africa|
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|Figure 3: Mode of preparation of remedies used in the treatment of ailments common among the residents of Seymour area in the Eastern Cape Province, South Africa|
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The application methods of herbal remedies also varied [Figure 4]. They included taking the decoctions, infusions, or fresh plant material orally for most reported ailments; application of plant extracts and paste directly on wounds and infected areas of skin; snuffing the powdered plant material for headaches and nose infections; smoking the powdered plant material for respiratory ailments; squeezing the warm plant extracts or sapping directly into the ear for ear infections; administering enema through the rectum for digestive problems; and inserting fresh leaves into the nostrils for blocked nose.
|Figure 4: Methods of preparation of traditional medicine. (a) Powdered traditional medicine which is used as a snuff; (b) Poultice which is applied on wounds or sores; (c and d) Leaf infusion and decoction|
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Some plants such as Aloe ferox, Alepidia amatymbica, Artemisia afra, Zantedeschia aethiopica, Arctotis arctotoides, H. odoratissimum, C. sativa, R. communis, A. tetracantha, Olea europaea, L. leonurus, M. heterophylla, and Xysmalobium undulatum were frequently mentioned by the traditional healers, herbalists, and villagers during the survey. In addition, it was interesting to note that Cyrtanthus obliquus, A. arctotoides, A. afra, H. odoratissimum, Emex australis, Cassipourea flanaganii, Solanum aculeastrum, Tulbaghia violacea, Asclepias fruticose, Bulbine frutescens, Opuntia vulgaris, L. leonurus, O. europaea, and S. henningsii were the most commonly used species in all the four villages (Phakamisa, old location, Izinyoka, and Joza). These plants have previously been cited in literature for the management and treatment of many ailments in South Africa, some of which were not mentioned by traditional healers, herbalists, and villagers in the study area. For example, A. afra is reported to be effective in treating bronchitis, TB, mumps, pneumonia, pimples, skin rashes, loss of appetite, colic, headache, ear ache, and intestinal worms,,, whereas L. leonorus is used against diabetes mellitus, eczema, epilepsy, delayed menstruation, intestinal worms, constipation, scorpion stings, snake bites, skin rashes, and boils.,,, A. ferox is a very popular medicinal plant used to treat sores, wounds, acne, burns, blisters, cold sores, cracked lips, insect bites, mouth ulcers, sunburn, rashes, and secondary infections of HIV. This is not surprising considering that a single plant species may contain several chemical compounds that may be active against a wide array of diseases. During the survey, some plants were reported to be more effective when used together with other plants for the treatment of a number of ailments, for example, C. asiatica was reported to be more effective when mixed with R. lanceolatus for the treatment of infertility and other related diseases.
| Conclusions|| |
This study has revealed important information on medicinal plants used by people, traditional healers, and herbalists of Seymour region in the Eastern Cape Province of South Africa to treat various ailments. It also demonstrates the vital role that medicinal plants play in the primary health care of these people. Fifty plant species, belonging to 29 families, are used to treat a wide range of ailments including respiratory and reproductive system diseases, musculoskeletal disorders, skin infections, ENT infections, ulcers, headache, gastrointestinal diseases, etc. It was interesting to note that some plant species were used to treat more than one ailments, for example, S. henningsii is used to treat TB, dysmenorrhea, constipation, and rheumatism. Some plants were effective when used in combination with others, for example, C. asiatica was effective when combined with R. lanceolatus for infertility. Leaves were reported to be the most commonly used plant parts, with decoction and infusion reported as the commonly used methods of preparation.
To know the proper medicinal value of some of these plants, studies have been undertaken and have confirmed their therapeutic effects. However, more researches on pharmacological, phytochemical, and toxicological studies of extracts prepared from some of these plants need to be conducted. This will help in the development of new plant-based drugs. This is part of a Master degree student work which will lead to writing a thesis which will be available in the university website for all users after submission.
The authors are grateful to the informants for providing information about their practice. This work would not have been possible without their help. Miss Philisiwe Makinana, though she could not complete her Master's degree, is acknowledged for compiling the information and preparing the manuscript.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Kamil M. Biological and pharmacological implications of flavonoids. In: Govil JN, Singh VK, Hashmi S, editors. A Review in Medicinal Plants: New Vistas of Research (Part 2). New Delhi: Today & Tomorrow's Printers and Publishers; 1993. p. 377-89.
Yadav JP, Kumar S, Siwach P. Folk medicine used in gynecological and other related problems by rural population of Haryana. Indian J Tradit Know 2006;5:323-6.
Olsen CS. The trade in medicinal and aromatic plants from central Nepal to Northern India. Econ Bot 1998;52:279-92.
Cunningham AB. African medicinal plants: Setting priorities at the interface between conservation and primary health care. People Plants Work Pap 1993;1:1-50.
Richter M. Traditional Medicines and Traditional Healers in South Africa. AIDS Law Project, Witwatersrand University, Johannesburg; 2003.
Taylor JL, Rabe T, McGaw LJ, Jäger AK, van Staden J. Towards the scientific validation of traditional medicinal plants. Plant Growth Regul 2001;34:23-37.
Mahwasane ST, Middleton L, Boaduo N. An ethnobotanical survey of indigenous knowledge on medicinal plants used by the traditional healers of the Lwamondo area, Limpopo province, South Africa. S Afr J Bot 2013;88:69-75.
Van Wyk BE, van Oudtshoorn B, Gericke N. Medicinal Plants of South Africa. 2nd
ed. Pretoria: Briza Publications; 1997.
Weideman L. An Investigation in to the Antibacterial Activities of Medicinal Plants Traditionally Used in the Eastern Cape to Treat Secondary Skin Infections Associated with Burn Wounds. MTech Thesis. Nelson Mandela Metropolitan University; 2005.
Dold AP, Cocks ML. The trade in medicinal plants in the Eastern Cape Province, South Africa. S Afr J Sci 2002;98:589-97.
Hirst M. The Healers Art: Cape Nguni diviners in the township of Grahamstown. PhD thesis, Rhodes University, Grahamstown; 1990.
Abdullahi AA. Trends and challenges of traditional medicine in Africa. Afr J Tradit Complement Altern Med 2011;8:115-23.
Light ME, Sparg SG, Stafford GI, van Staden J. Riding the wave: South Africa's contribution to ethnopharmacological research over the last 25 years. J Ethnopharmacol 2005;100:127-30.
Street RA, Prinsloo G. Commercially important medicinal plants of South Africa: A review. J Chemistry 2013;2013:205048. Available from: http://dx.doi.org/10.1155/2013/205048
. [Last accessed on 2018 Jul 18].
Madikizela B, Ndhlala AR, Finnie JF, Van Staden J. Ethnopharmacological study of plants from pondoland used against diarrhoea. J Ethnopharmacol 2012;141:61-71.
Klos M, van de Venter M, Milne PJ, Traore HN, Meyer D, Oosthuizen V, et al. In vitro
anti-HIV activity of five selected South African medicinal plant extracts. J Ethnopharmacol 2009;124:182-8.
Dyubeni L, Buwa LV. An ethnobotanical study of plants used for the treatment of ear, nose and throat (ENT) infections in Nkonkobe Municipality, South Africa. J Med Plants Res 2012;6:2721-6.
Otang WM, Grierson DS, Ndip RN. Ethnobotanical survey of medicinal plants used in the management of opportunistic fungal infections in HIV/AIDS patients in the Amathole district of the Eastern Cape province, South Africa. J Med Plants Res 2012;6:2071-80.
Afolayan AJ, Grierson DS, Mbeng WO. Ethnobotanical survey of medicinal plants used in the management of skin disorders among the Xhosa communities of the Amathole district, Eastern Cape, South Africa. J Ethnopharmacol 2014;153:220-32.
Lawal IO, Grierson DS, Afolayan AJ. Phytotherapeutic information on plants used for the treatment of tuberculosis in Eastern Cape province, South Africa. Evid Based Complement Alternat Med 2014;2014:735423.
Sheng-Ji P. Ethnobotanical approaches of traditional medicine studies: Some experiences from Asia. Pharm Biol 2001;39 Suppl 1:74-9.
Sofowora A. Medicinal Plants and Traditional Medicine in Africa. 2nd
ed. Ibadan, Nigeria: Spectrum Books; 1993.
Bussmann RW, Gilbreath GG, Solio J, Lutura M, Lutuluo R, Kunguru K, et al.
Plant use of the Maasai of Sekenani Valley, Maasai Mara, Kenya. J Ethnobiol Ethnomed 2006;2:22.
Van Wyk BE, Gericke N. People's Plants: A Guide to Useful Plants of Southern Africa. Pretoria: Briza Publications; 2002.
Masika PJ, Afolayan AJ. An ethnobotanical study of plants used for the treatment of livestock diseases in the Eastern Cape Province, South Africa. Pharm Biol 2003;41:16-21.
Jovel EM, Cabanillas J, Towers GH. An ethnobotanical study of the traditional medicine of the Mestizo people of Suni Miraño, Loreto, Peru. J Ethnopharmacol 1996;53:149-56.
Trotter RT, Logan MH. Informant consensus: A new approach for identifying potentially effective medicinal plants. In: Etkin NL, editor. Plants in Indigenous Medicine and Diet, Behavioural Approaches. Bredford Hills, NY: Redgrave Publishing Company; 1986.
Zlatković BK, Bogosavljević SS, Radivojević AR, Pavlović MA. Traditional use of the native medicinal plant resource of Mt. Rtanj (Eastern Serbia): Ethnobotanical evaluation and comparison. J Ethnopharmacol 2014;151:704-13.
Amujoyegbe OO, Idu M, Agbedahunsi JM, Erhabor JO. Ethnomedicinal survey of medicinal plants used in the management of sickle cell disorder in Southern Nigeria. J Ethnopharmacol 2016;185:347-60.
Bouyahya A, Abrini J, Et-Touys A, Bakri Y, Dakka N. Indigenous knowledge of the use of medicinal plants in the North-West of Morocco and their biological activities. Eur J Integr Med 2017;13:9-25.
Güzel Y, Güzelşemme M, Miski M. Ethnobotany of medicinal plants used in Antakya: A multicultural district in Hatay Province of Turkey. J Ethnopharmacol 2015;174:118-52.
Chethan J, Kumara KK, Niranjana SR, Prakash HS. Evaluation of antioxidant and antibacterial activities of methanolic flower extract of Wedelia trilobata
(L.) hitch. Afr J Biotech 2012;11:9829-34.
Jansen O, Tits M, Angenot L, Nicolas JP, De Mol P, Nikiema JB, et al.
Anti-plasmodial activity of Dicoma tomentosa
) and identification of urospermal A-15-O-acetate as the main active compound. Malar J 2012;11:289.
Orwa JA, Ngeny L, Mwikwabe NM, Ondicho J, Jondiko IJ. Antimalarial and safety evaluation of extracts from Toddalia asiatica
(L) lam. (Rutaceae
). J Ethnopharmacol 2013;145:587-90.
Passero LF, Laurenti MD, Santos-Gomes G, Soares Campos BL, Sartorelli BP, Lago JH.In vivo
antileishmanial activity of plant-based secondary metabolites. In: Rai MK, Kon KV, editors. Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components. 1st
ed. Oxford: Academic Press; 2013. p. 95-107.
Orhan N, Hoçbaç S, Orhan DD, Asian M, Ergun F. Enzyme inhibitory and radical scavenging effects of some antidiabetic plants of Turkey. Iran J Basic Med Sci 2014;17:426-32.
Amani A, Abdalqawi M, Sanaa AK, Monerah RA, Rehab S, Zain ME. Pharmacological activities for the extract and isolated compounds of Euphorbia cuneatav
VHL. Int J Biol Pharm Allied Sci 2016;5:319-31.
Juveriyah K, Durai M, Agaath H, Vijaya A. Review of the phytochemical and pharmacological activities of Euphorbia hirta
Linn. Pharmacogn J 2016;8:310-3.
Mali PY, Panchal SS. Euphorbia tirucalli
L.: Review on morphology, medicinal uses, phytochemistry and pharmacological activities. Asian Pac J Trop Biomed 2017;7:603-13.
Noufou O, Wamtinga SR, André T, Christine B, Marius L, Emmanuelle HA, et al.
Pharmacological properties and related constituents of stem bark of Pterocarpus erinaceus
). Asian Pac J Trop Med 2012;5:46-51.
Panthati MK, Rao KN, Sandhya SI, Banji D. A review on phytochemical, ethnomedical and pharmacological studies on genus Sophora, Fabaceae
. Braz J Pharmacogn 2012;22:1145-54.
El-Nashar HA, Eldahshan O, Singab AN. The tribe Caesalpinieae
): An updated review on pharmacological aspects. Med Aromat Plants 2015;4:1-4.
Singh G, Sharma PK, Dudhe R, Singh S. Biological activities of Withania somnifera
. Ann Biol Res 2010;1:56-63.
Wang P, Su Z, Yuan W, Deng G, Li S. Phytochemical constituents and pharmacological activities of Eryngium L
). Pharm Crops 2012;3:99-120.
Patel K, Singh RB, Patel DK. Medicinal significance, pharmacological activities, and analytical aspects of solasodine: A concise report of current scientific literature. J Acute Dis 2013;2:92-8.
Prashith KT, Raghvandra HL. Medicinal uses, phytochemistry and pharmacological activities of Antigonon leptopus
hook and Arn. (Polygonaceae
): A review. J Chem Pharm Res 2018;10:103-10.
Sahebkar A, Iranshahi M. Biological activities of essential oils from the genus Ferula
). Asian Biomed 2010;4:835-47.
Sadat-Hosseini M, Farajpour M, Boroomand N, Solaimani-Sardou F. Ethnopharmacological studies of indigenous medicinal plants in the South of Kerman, Iran. J Ethnopharmacol 2017;199:194-204.
Mwangi VI, Mumo RM, Nyachieo A, Onkoba N. Herbal medicine in the treatment of poverty associated parasitic diseases: A case of sub-Saharan Africa. J Herb Med 2017;10:1-7.
Silambarasan R, Sureshkumar J, Krupa J, Amalraj S, Ayyanar M. Traditional herbal medicines practiced by the ethnic people in Sathyamangalam forests of Western Ghats, India. Eur J Integr Med 2017;16:61-72.
Buwa LV, Afolayan AJ. Antimicrobial activity of some medicinal plants used for the treatment of tuberculosis in the Eastern Cape Province, South Africa. Afr J Biotechnol 2009;8:6683-7.
Coopoosamy RM, Naidoo KK. An ethnobotanical survey of medicinal plants used by traditional healers in Durban, South Africa. Afr J Pharm Pharmacol 2012;6:818-23.
Van Wyk BE, van Oudtshoorn B, Gericke N. Medicinal Plants of South Africa. Revised Edition. Cape Town: Briza Publications; 2000.
Bienvenu E, Amabeoku GJ, Eagles PK, Scott G, Springfield EP. Anticonvulsant activity of aqueous extract of Leonotis leonurus
. Phytomedicine 2002;9:217-23.
Jäger AK, Hutchings A, van Staden J. Screening of Zulu medicinal plants for prostaglandin-synthesis inhibitors. J Ethnopharmacol 1996;52:95-100.
Ososki AL, Lohr P, Reiff M, Balick MJ, Kronenberg F, Fugh-Berman A, et al.
Ethnobotanical literature survey of medicinal plants in the Dominican republic used for women's health conditions. J Ethnopharmacol 2002;79:285-98.
Njume C, Afolayan AJ, Ndip RN. Diversity of plants used in the treatment of Helicobacter pylori
associated morbidities in the nkonkobe municipality of the Eastern Cape Province of South Africa. J Med Plants Res 2011;5:3146-51.
[Figure 1], [Figure 2], [Figure 3], [Figure 4]
[Table 1], [Table 2], [Table 3]
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||Toxicological Evaluation of Aqueous Stem Bark Extract of Guiera senegalensis on Wistar Rats
| ||Diowato TITUS, Maryam Usman AHMED, Isaac John UMARU |
| ||International Journal of Traditional and Complementary Medicine Research. 2022; : 117 |
|[Pubmed] | [DOI]|
||A Review on Medicinal Plants Used in the Management of Headache in Africa
| ||Ebenezer Kwabena Frimpong, John Awungnjia Asong, Adeyemi Oladapo Aremu |
| ||Plants. 2021; 10(10): 2038 |
|[Pubmed] | [DOI]|
||Evaluating Peptides of Picrorhiza kurroa and Their Inhibitory Potential against ACE, DPP-IV, and Oxidative Stress
| ||Shweta Thakur, Jyoti Chhimwal, Robin Joshi, Manglesh Kumari, Yogendra Padwad, Rajiv Kumar |
| ||Journal of Proteome Research. 2021; 20(8): 3798 |
|[Pubmed] | [DOI]|
||Gastroprotective Effects of Methanolic Leaves and Stem Extracts of
Sphagneticola trilobata on Indomethacin-Induced Gastric Ulcer in Rats
| ||Kartik Singhal, Chandana Majee, Bhavani Pentela, Vikas Sharma |
| ||Asian Journal of Chemistry. 2021; 34(1): 111 |
|[Pubmed] | [DOI]|
||Traditional use of ethnomedicinal plants among people of Kapurthala District, Punjab, India
| ||Jaskirat Kaur, Rajinder Kaur, AvinashKaur Nagpal |
| ||Pharmacognosy Magazine. 2020; 16(68): 69 |
|[Pubmed] | [DOI]|