Home | About PM | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |  Login 
Pharmacognosy Magazine
Search Article 
Advanced search 
Year : 2011  |  Volume : 7  |  Issue : 27  |  Page : 193-199

Evaluation of phytochemical composition and antioxidant capacity of a decoction containing Adenanthera pavonina L. and Thespesia populnea L.

Department of Biochemistry and Molecular Biology, University of Colombo, Sri Lanka

Correspondence Address:
Preethi Soysa
Department of Molecular Biology and Biochemistry, Faculty of Medicine, University of Colombo, Colombo 08
Sri Lanka
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-1296.84229

Rights and Permissions

Background: A decoction prepared with barks of Adenanthera pavonina and Thespesia populnea is a herbal formulation which has been prescribed in Sri Lanka in the treatment of cancer patients for many years. This study was designed to investigate its phytochemical and antioxidant properties. Materials and Methods: The total phenolics and flavonoids were determined using Folin-Ciocalteau and aluminum chloride colorimetric methods, respectively. Gallic acid content in the decoction was determined using high-performance liquid chromatography. The antioxidant properties were evaluated by 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical assay, nitric oxide scavenging assay, deoxyribose method, and the reducing power of the decoction. Results: The concentration of total phenols, flavonoids, and gallic acid of the decoction were 34.13 ± 3.54 w/w % gallic acid equivalents, 41.37 ± 0.57 w/w % of (-)-Epigallocatechin gallate equivalents, and 0.58 ± 0.24 mg/g, respectively. The EC50 for DPPH, nitric oxide scavenging, and deoxyribose assays were 7.24 ± 0.50, 14.02 ± 0.66, and 53.21 ± 2.82 μg/ml, respectively. Reducing power of the decoction increased with the concentration. Conclusion: These investigations suggested that the decoction prepared with A. pavonina and T. populnea can be a potential source of nutraceuticals with antioxidant activity.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded159    
    Comments [Add]    
    Cited by others 14    

Recommend this journal