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RESEARCH ARTICLE
Year : 2009  |  Volume : 5  |  Issue : 19  |  Page : 23-27

Antidiarrheal activity of Cynodon Dactylon. pers


Department of Pharmacognosy, G. Pulla reddy College of Pharmacy, Mehdipatnam, Hyderabad-500028, Andhra Pradesh, India

Correspondence Address:
Madhava B Reddy
Department of Pharmacognosy, G. Pulla reddy College of Pharmacy, Mehdipatnam, Hyderabad-500028, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


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Cynodon dactylon pers (fam. Poaceae) whole plant is used in traditional system of medicine for the treatment of diarrhea. In the present investigation hexane, dichloromethane, ethyl acetate and methanol extracts of Cynodon dactylon whole plant were tested for anti diarrheal activity on castor oil induced diarrhea, gastro intestinal motility by charcoal meal and entero pooling models in albino rats. Methanol extract exhibited considerable reduction in inhibition of castor oil induced diarrhea. Methanol extract also showed a significant decrease in gastrointestinal motility by charcoal meal and decrease in weight of intestinal contents in enteropooling models. These results indicate that the plant possess good anti diarrheal activity.


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