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  Indian J Med Microbiol
 

Figure 1: Artemisinin synthesis pathways in Artemisia annua. The enzymes shown in red belong to mevalonate pathway. The 2-C-methyl-D-erythritol 4-phosphate pathway enzymes are shown in green oval cartoon. The enzymes for artemisinin biosynthesis start from farnesyl diphosphate (farnesyl pyrophosphate), an intermediate product of terpenoid metabolism. The arrows between mevalonate pathway and 2-C-methyl-D-erythritol 4-phosphate pathway demonstrate the crosstalk between these two pathways during artemisinin biosynthesis. The enzymes starting from the branch point (assigned with a cross sign below them) showing two putative sideway pathway enzymes in terpenoid metabolism

Figure 1: Artemisinin synthesis pathways in <i>Artemisia annua</i>. The enzymes shown in red belong to mevalonate pathway. The 2-C-methyl-D-erythritol 4-phosphate pathway enzymes are shown in green oval cartoon. The enzymes for artemisinin biosynthesis start from farnesyl diphosphate (farnesyl pyrophosphate), an intermediate product of terpenoid metabolism. The arrows between mevalonate pathway and 2-C-methyl-D-erythritol 4-phosphate pathway demonstrate the crosstalk between these two pathways during artemisinin biosynthesis. The enzymes starting from the branch point (assigned with a cross sign below them) showing two putative sideway pathway enzymes in terpenoid metabolism