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  Indian J Med Microbiol
 

Figure 3: Immunofluorescence analysis of Keap-1 and Nrf-2 in mammary tissue of all experimental animals. n = 8. DAPI: florescent-blue (nucleus); Cy3: red; Cy5: dark blue. (a) Degradation of Keap-1 after TAX treatment to DMBA induced mammary cancer tissue. Keap-1 degradation is represented in a closer view (small extended slides). For the analysis immunofluorescence staining (×160) was used. (b) TAX treated experimental groups revealed Keap-1 dependent Nrf2 nuclear translocation (×170). The translocation of Nrf2 from cytosol to nucleus is represented in a closer view (small extended slides). DMBA: 7,12-dimethylbenz (a) anthracene; TAX: Taxifolin; Keap-1: Kelch-like ECH-associated protein 1; Nrf2: Nuclear factor erythroid 2

Figure 3: Immunofluorescence analysis of Keap-1 and Nrf-2 in mammary tissue of all experimental animals. <i>n</i> = 8. DAPI: florescent-blue (nucleus); Cy3: red; Cy5: dark blue. (a) Degradation of Keap-1 after TAX treatment to DMBA induced mammary cancer tissue. Keap-1 degradation is represented in a closer view (small extended slides). For the analysis immunofluorescence staining (×160) was used. (b) TAX treated experimental groups revealed Keap-1 dependent Nrf2 nuclear translocation (×170). The translocation of Nrf2 from cytosol to nucleus is represented in a closer view (small extended slides). DMBA: 7,12-dimethylbenz (a) anthracene; TAX: Taxifolin; Keap-1: Kelch-like ECH-associated protein 1; Nrf2: Nuclear factor erythroid 2