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  Indian J Med Microbiol
 

Figure 5: Effect of the sponge extract on DNA fragmentation and nuclear morphology of MCF-7 cells. (A) Gel electrophoresis result showing effect of sponge extract on DNA fragmentation of MCF-7 cell line. Lane 1: control; Lane 2: marker; Lane 3: 25 µg/ml extract-treated cells; Lane 4: 50 µg/ml extract-treated cells; Lane 5: 100 µg/ml extract-treated cells. (B–E) Nuclear morphology changes of MCF-7 cells at different concentration of sponge extract treatment: (B) control (0 µg/ml), (C) 25 µg/ml, (D) 50 µg/ml, and (E) 100 µg/ml of extract-treated cells

Figure 5: Effect of the sponge extract on DNA fragmentation and nuclear morphology of MCF-7 cells. (A) Gel electrophoresis result showing effect of sponge extract on DNA fragmentation of MCF-7 cell line. Lane 1: control; Lane 2: marker; Lane 3: 25 µg/ml extract-treated cells; Lane 4: 50 µg/ml extract-treated cells; Lane 5: 100 µg/ml extract-treated cells. (B–E) Nuclear morphology changes of MCF-7 cells at different concentration of sponge extract treatment: (B) control (0 µg/ml), (C) 25 µg/ml, (D) 50 µg/ml, and (E) 100 µg/ml of extract-treated cells