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  Indian J Med Microbiol
 

Figure 4: Effect of treadmill exercise and epicatechin on amyloid-β plaque formation and soluble amyloid-β production in the hippocampus of amyloid precursor protein/presenilin 1 mice. (a) Amyloid-β immunoreactive plaques formation in the hippocampus of amyloid precursor protein/presenilin 1 mice. Scale bar = 200 μm. (b) Quantification of the amyloid-β-positive plaques number. (c) Soluble amyloid-β1-40 and amyloid-β1-42 production by enzyme-linked immunosorbent assay kit. Values are expressed as mean ± standard error n = 8. Statistics (b and c): *P < 0.05 compared with wild-type littermates; #P < 0.05 compared with transgenic

Figure 4: Effect of treadmill exercise and epicatechin on amyloid-β plaque formation and soluble amyloid-β production in the hippocampus of amyloid precursor protein/presenilin 1 mice. (a) Amyloid-β immunoreactive plaques formation in the hippocampus of amyloid precursor protein/presenilin 1 mice. Scale bar = 200 μm. (b) Quantification of the amyloid-β-positive plaques number. (c) Soluble amyloid-β1-40 and amyloid-β1-42 production by enzyme-linked immunosorbent assay kit. Values are expressed as mean ± standard error <i>n</i> = 8. Statistics (b and c): *<i>P</i> < 0.05 compared with wild-type littermates; #<i>P</i> < 0.05 compared with transgenic