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  Indian J Med Microbiol
 

Figure 2: Cucumis melo ssp. agrestis var. agrestis fractions (Cucumis melo ssp. agrestis var. agrestis water fraction and Cucumis melo ssp. agrestis var. agrestis hexane fraction) attenuated body weight gain, improved dyslipidemia and hyperglycemia without altering diet intake. The direct analysis in real time-mass spectrometry was recorded on a JEOL-Accu TOF JMS-T100LC mass spectrometer having a direct analysis in real time source. The samples were subjected as such in front of direct analysis in real time source. Dry Helium gas was used for ionization at 4 L/min flow rate and source temperature kept at 350°C. The orifice 1 was set at 28 V and spectra collected as average of 6-8 scan. (a) Direct analysis in real time-mass spectrometry fingerprint of both fractions. Syrian golden hamsters (n = 8), fed with chow or high fat diet were kept on either fenofibrate (100 mg/kg), on Cucumis melo ssp. agrestis var. agrestis fruit extract (50 mg/kg) or on Cucumis melo ssp. agrestis var. agrestis hexane fraction (50 mg/kg) for 7 days. (b) Body weight of chow or high fat diet fed dyslipidemic hamsters treated with or without Cucumis melo ssp. agrestis var. agrestis fractions. Hamsters were treated with Cucumis melo ssp. agrestis var. agrestis fractions or fenofibrate for 7 days and body weight was measured every day in morning before providing diet. (c) Average food intake amount of chow and high fat diet diet mice in 10 days feeding. Diet intake was recorded every day. (d) Total cholesterol. (e) Triglyceride (f) low-density lipoprotein-cholesterol. (g) high-density lipoprotein-cholesterol cholesterol. (h) Very low‐density lipoprotein-cholesterol. (i) High-density lipoprotein-cholesterol cholesterol/total cholesterol ratio. (j) Serum Glucose. Values are means (n = 8), with their standard error of mean represented by vertical bars. Mean values were significantly different from the high fat diet diet-fed animals (one-way analysis of variance): *P < 0·05, **P < 0·01, ***P < 0.001. *Denotes that the mean values are significantly different

Figure 2: <i>Cucumis melo ssp. agrestis var. agrestis</i> fractions (<i>Cucumis melo ssp. agrestis var. agrestis water fraction</i> and <i>Cucumis melo ssp. agrestis var. agrestis hexane fraction</i>) attenuated body weight gain, improved dyslipidemia and hyperglycemia without altering diet intake. The direct analysis in real time-mass spectrometry was recorded on a JEOL-Accu TOF JMS-T100LC mass spectrometer having a direct analysis in real time source. The samples were subjected as such in front of direct analysis in real time source. Dry Helium gas was used for ionization at 4 L/min flow rate and source temperature kept at 350°C. The orifice 1 was set at 28 V and spectra collected as average of 6-8 scan. (a) Direct analysis in real time-mass spectrometry fingerprint of both fractions. Syrian golden hamsters (<i>n</i> = 8), fed with chow or high fat diet were kept on either fenofibrate (100 mg/kg), on <i>Cucumis melo ssp. agrestis var. agrestis fruit extract</i> (50 mg/kg) or on <i>Cucumis melo ssp. agrestis var. agrestis hexane fraction</i> (50 mg/kg) for 7 days. (b) Body weight of chow or high fat diet fed dyslipidemic hamsters treated with or without <i>Cucumis melo ssp. agrestis var. agrestis</i> fractions. Hamsters were treated with <i>Cucumis melo ssp. agrestis var. agrestis</i> fractions or fenofibrate for 7 days and body weight was measured every day in morning before providing diet. (c) Average food intake amount of chow and high fat diet diet mice in 10 days feeding. Diet intake was recorded every day. (d) Total cholesterol. (e) Triglyceride (f) low-density lipoprotein-cholesterol. (g) high-density lipoprotein-cholesterol cholesterol. (h) Very low‐density lipoprotein-cholesterol. (i) High-density lipoprotein-cholesterol cholesterol/total cholesterol ratio. (j) Serum Glucose. Values are means (<i>n</i> = 8), with their standard error of mean represented by vertical bars. Mean values were significantly different from the high fat diet diet-fed animals (one-way analysis of variance): *<i>P</i> < 0·05, **<i>P</i> < 0·01, <i>***P</i> < 0.001. *Denotes that the mean values are significantly different