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  Indian J Med Microbiol
 

Figure 3: Effect of Yin-Chen-Hao-Tang (YCHT) on the liver microstructure in cirrhotic rats. (a) ×2250. (b) ×18000, observed by transmission electron microscope. In the sham group, biliary epithelial cells (BECs) formed the bile duct cavity, and there were many microvilli, but little collagen deposition around the BECs. In the saline + bile duct ligation (BDL) group, there was cholestasis in both hepatocytes and BECs, fewer microvilli, and bile thrombi appeared. Extracellular matrix (ECM) deposition and desmocyte aggregation could be seen around the bile duct, and there was cholestasis in hepatocytes. In the YCHT + BDL group, there was less cholestasis in hepatocytes and BECs, no bile thrombus, and less ECM deposition around bile duct compared with the saline + BDL group (H: Hepatocyte; B: Biliary epithelial cell; E: Extracellular matrix)

Figure 3: Effect of Yin-Chen-Hao-Tang (YCHT) on the liver microstructure in cirrhotic rats. (a) ×2250. (b) ×18000, observed by transmission electron microscope. In the sham group, biliary epithelial cells (BECs) formed the bile duct cavity, and there were many microvilli, but little collagen deposition around the BECs. In the saline + bile duct ligation (BDL) group, there was cholestasis in both hepatocytes and BECs, fewer microvilli, and bile thrombi appeared. Extracellular matrix (ECM) deposition and desmocyte aggregation could be seen around the bile duct, and there was cholestasis in hepatocytes. In the YCHT + BDL group, there was less cholestasis in hepatocytes and BECs, no bile thrombus, and less ECM deposition around bile duct compared with the saline + BDL group (H: Hepatocyte; B: Biliary epithelial cell; E: Extracellular matrix)