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  Indian J Med Microbiol
 

Figure 5: Effects of Fu-Fang-Lu-Jiao-Shuang (FFLJS) on the production of tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1) β, IL-17 and prostaglandin E-2 (PGE-2) in serum. The amounts of TNF-α, IL-1 β, IL-17 and PGE-2 in serum of collagen induced arthritis (CIA) mice 7 weeks after the first collagen injection were obviously increased. Treatment with 125 or 500 mg/kg of FFLJS for 4 weeks decreased significantly the levels of TNF-α, IL-1 β, IL-17 and PGE-2. Data are expressed as means ± standard error of the mean; ##P < 0.01 compared with sample of normal group, *P < 0.05, **P < 0.01 compared with the CIA group (n = 10 in each group)

Figure 5: Effects of Fu-Fang-Lu-Jiao-Shuang (FFLJS) on the production of tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1) β, IL-17 and prostaglandin E-2 (PGE-2) in serum. The amounts of TNF-α, IL-1 β, IL-17 and PGE-2 in serum of collagen induced arthritis (CIA) mice 7 weeks after the first collagen injection were obviously increased. Treatment with 125 or 500 mg/kg of FFLJS for 4 weeks decreased significantly the levels of TNF-α, IL-1 β, IL-17 and PGE-2. Data are expressed as means ± standard error of the mean; ##<i>P</i> < 0.01 compared with sample of normal group, *<i>P</i> < 0.05, **<i>P</i> < 0.01 compared with the CIA group (<i>n</i> = 10 in each group)